Results 41 to 50 of about 31,983 (264)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Implementasi Fuzzy Analytical Hierarchy Process Menggunakan Database Maria DB

Jurnal EECCIS (Electrics, Electronics, Communications, Controls, Informatics, Systems), 2019
Abstrak–-Paper ini berisi tetntang implementasi metode fuzzy Analytical Hierarchy Process (F-AHP) pada database mariaDB. Untuk membuat suatu Decision Support System (DSS) yang dinamis maka metode Analytical Hierarchy Process (AHP) dibuat didalam ...
Anang Aris Widodo, Sholeh Hadi Pramono, Harry Soekotjo Dachlan   +2 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Providing a decision model for determining evaluation purpose, the most important factor and selecting strategic supplier in supply chain by paralytic network process approach [PDF]

مطالعات مدیریت بهبود و تحول, 2010
The main purpose of this research is to provide a good insight into the use of analytic network process (ANP) that is a multiple criteria decision-making methodology in evaluating supplier selection problems.
behrooz dari nokorani, mohammad bagherzadeh azar   +1 more
doaj  

Selecting equipment using a hybrid of AHP and PROMETHEE [PDF]

Management Science Letters, 2013
, Pages 1767-1772 and PDF (194 K)Abstract: Having appropriate technology is an important managerial decision in today’s manufacturing industry and to choose a good technology, we need to consider various alternatives.
Mohammad Sadegh Horri, Porya Moradi
doaj   +1 more source

Risk Assessment of Accidental Fire Breakdown in a Residential Area of Khulna City, Bangladesh

Journal of Engineering Science, 2021
The research aimed at determining the risk of fire hazard of the settlements in the area of Khalishpur, Khulna which is close to three oil depots and two power stations. The maintainence of land use zonal variance is completely absent in this area.
Sadia Shama, Alif Sanim Shurid , Md. Nazmul Haque   +2 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Design of Decision Support System Selection of Beach Tourism Object in GunungKidul using Fuzzy AHP Method

IJID (International Journal on Informatics for Development), 2018
The tourism industry is currently one of the important assessments for a certain region. Gunungkidul has a lot of of beach tourism potentials until visitors are confused to choose the right beach.
Yudi Istianto, Bambang Sugiantoro
doaj   +1 more source