Results 61 to 70 of about 31,983 (264)
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Mapping disaster vulnerability in India using analytical hierarchy process
Disasters are the coincidences between hazardous events, elements at risk, and conditions of vulnerability. Vulnerability integrates social and environmental systems to reduce the intensity and frequency of these risks.
Anusheema Chakraborty, P.K. Joshi
doaj +1 more source
A Clarification of “Remarks on the Analytic Hierarchy Process” [PDF]
The replies by Saaty (1990) and by Harker and Vargas (1990) to my remarks on the Analytic Hierarchy Process (Dyer 1990) are useful in focusing attention on areas of disagreement regarding the AHP, and provide readers with sufficient information to form their own opinions.
openaire +1 more source
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
Pest control in vegetable cropping by using chemical pesticides intensively can have a negative impact on human health and environmental health. The IPM approach was an innovation that farmers need to adapt to reduce the use of chemical pesticides. This
Anes Putri Octasari +2 more
doaj +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
EVALUASI PEMILIHAN PENYEDIA JASA KURIR BERDASARKAN METODE ANALYTICAL HIERARCHY PROCESS (AHP)
Logistics activity plays an important role in the business process where there is a distribution process to deliver product from the manufacturer / seller to the consumer.
Juli Astuti, Erika Fatma
doaj +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley +1 more source

