Results 31 to 40 of about 1,975,844 (241)

Internalizing International Trade Law: A Critical Analysis of the Canadian Free Trade Agreement’s National Treatment Jurisprudence

open access: yesOsgoode Hall Law Journal, 2021
The Canadian Free Trade Agreement 2017 (CFTA), which replaced the Agreement on Internal Trade 1995 (AIT), provides a forum to resolve internal trade disputes against provinces, territories, and the federal government.
Ryan Manucha
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Genealogy of the formation of knowledge of the principles of jurisprudence in Imami religious thought and its independence from jurisprudence and theology

open access: yesمطالعات تطبیقی فقه و اصول مذاهب, 2021
The formation of the knowledge of principles in an ijtihad manner, in Islamic religious thought, is a turning point and a great turning point from pre-theoretical jurisprudence to institutional jurisprudence, which is among the Sunnis in the late second ...
akram abdolahpur
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

The Rule: The Establishment of Safety up to Maximum Possible Capacity and its Contemporary Applications

open access: yesالإيضاح, 2023
This study aims to highlight the most important rule of Islamic Jurisprudence and its implication in the contemporary context through a detailed description of such rules. It also examines the use of inductive, descriptive and analytical approach to such
Salem Abdullah Abu Mukhadda Abu Mukhadda   +1 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Concept of Ignorance [PDF]

open access: yesپژوهش‌نامه حقوق اسلامی, 2012
The concept of ignorance “jahl” frequently occurs in most of the disciplines of law especially private and criminal law and in some relevant disciplines such as jurisprudence and its principles.
ruhollah akhoondi
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Anglo-American legal positivism: Stages of formation and development

open access: yesRUDN Journal of Law
Anglo-American legal positivism is an influential trend in modern legal thought. Understanding this framework is crucial not only for addressing gaps in scientific knowledge within political and legal doctrines but also for applying relevant developments
Maxim D. Gorbunov
doaj   +1 more source

النظام الفيدرالي في العراق  بين العرب والكورد   ـ دراسة تحليلية في فقه السياسة الشرعية ـ

open access: yesZanco Journal of Humanity Sciences, 2018
There is a great deal of disagreement between the Iraqi intellectuals and sometimes skip to differences and mutual accusations because of the issue of federalism whereas of its feasibility and applicability between the two basic nationalities ( Arabs ...
حسن خالد مصطفى محمود المفتي
doaj   +1 more source

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