Results 41 to 50 of about 1,895,848 (278)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Anglo-American legal positivism: Stages of formation and development

open access: yesRUDN Journal of Law
Anglo-American legal positivism is an influential trend in modern legal thought. Understanding this framework is crucial not only for addressing gaps in scientific knowledge within political and legal doctrines but also for applying relevant developments
Maxim D. Gorbunov
doaj   +1 more source

The Principles of Governmental Jurisprudence as the Logic of Deducing Governmental Jurisprudence [PDF]

open access: yesعلوم سیاسی
Today, with the evolution of social systems, the continuous development of human life, and the growing complexity of issues, a vast array of subjects has emerged for jurisprudence to address.
Sayez Sajad Izdehi, Mostafa Rezaei
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Strasbourg Jurisprudence in Domestic Courts under the Human Rights Act [PDF]

open access: yes, 2009
Section 2 of the Human Rights Act 1998 enjoins UK domestic courts to ‘take into account’ Strasbourg jurisprudence but does not bind them to it. Neither does s.2 oblige domestic courts to follow it, imitate it or restrict themselves to it.
TYRRELL, HELENE,GRACE
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Development of the Concept of Arrogance in Various Periods of Shia Jurisprudence [PDF]

open access: yesمطالعات زن و خانواده, 2016
This research aimed at the development of the concept of arrogance in various periods of Shia jurisprudence based on a descriptive–analytical method and tried to investigate the problems aroused regarding couple’s arrogance based on the Islamic ...
Maryam Ahmadieh, Mohammad Eshaghi
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Evaluation of the jurisprudence course included in the book of Islamic studies for the upper classes in the light of the textbook quality standards

open access: yesJournal of Umm Al-Qura University for Educational and Psychological Sciences, 2022
This study aimed to identify the degree of observance of the Jurisprudence Course in the Islamic studies textbook for upper grades in the primary stage for standards the quality of the textbook.
Ahmed Al-Qarni
doaj   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

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