Results 121 to 130 of about 3,655,467 (372)

A Progressive Visual Analytics Tool for Incremental Experimental Evaluation [PDF]

arXiv, 2019
This paper presents a visual tool, AVIATOR, that integrates the progressive visual analytics paradigm in the IR evaluation process. This tool serves to speed-up and facilitate the performance assessment of retrieval models enabling a result analysis through visual facilities.
arxiv  

A multiscale Molecular Dynamics approach to Contact Mechanics

, 2006
The friction and adhesion between elastic bodies are strongly influenced by the roughness of the surfaces in contact. Here we develop a multiscale molecular dynamics approach to contact mechanics, which can be used also when the surfaces have roughness ...
Persson, B. N. J., Tartaglino, U., Yang, C.   +2 more
core   +1 more source

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

Molecular Oncology, Volume 19, Issue 5, Page 1386-1403, May 2025.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale, Li Li, J. Kyle Bruner, Melody Chou, Bao Nguyen, Jaesung Seo, Ruiqi Zhu, Mark J. Levis, Christine A. Pratilas, Donald Small   +9 more
wiley   +1 more source

Fundamentals and Applications of Fluid Mechanics and Acoustics in Biomedical Engineering

Bioengineering
The field of biomedical engineering has experienced important recent advances in experimental, computational, and analytical research in fluid mechanics and acoustics [...]
Iris Little, Ephraim Gutmark
doaj   +1 more source

Replenishing co‐downregulated miR‐100‐5p and miR‐125b‐5p in malignant germ cell tumors causes growth inhibition through cell cycle disruption

Molecular Oncology, Volume 19, Issue 4, Page 1203-1228, April 2025.
MiR‐99a‐5p/miR‐100‐5p (functionally identical) and miR‐125b‐5p microRNAs are downregulated in malignant germ cell tumors (GCTs). Combination replenishment of these microRNAs using mimics resulted in growth inhibition in representative cell lines, with consequent downregulation of target genes involved in cell cycle (confirmed by flow cytometry) and ...
Marta Ferraresso, Shivani Bailey, Luz Alonso‐Crisostomo, Dawn Ward, Christos Panayi, Zachary G. L. Scurlock, Harpreet K. Saini, Stephen P. Smith, James C. Nicholson, Anton J. Enright, Cinzia G. Scarpini, Nicholas Coleman, Matthew J. Murray   +12 more
wiley   +1 more source

Cross-Coupled Heat and Moisture Transport Part 2/1: Applications in Mechanics

Journal of Mechanical Engineering, 2018
Based on the theory laid down in the Part 1 [1] in this paper we are going to display applications in physics and especially in mechanics. After a short summary on coupled fields in mechanics, we generally analyze the analogies in mechanics.
Andras Szekeres, Balazs Fekete
doaj   +1 more source

Analytical Mechanics and Field Theory [PDF]

arXiv
Lecture notes for a one-semester master-level course on analytical mechanics and classical field theory, covering: 0 Mathematical Introduction, 1 Lagrangian Mechanics, 2 Application: Motion in Central Fields, 3 Hamiltonian Mechanics, 4 Application: Oscillations of Mechanical Systems, 5 Application: Relativistic Mechanics, 6 Geometry of Classical ...
arxiv  

Self-Similar Crossover in Statistical Physics

, 2000
An analytical method is advanced for constructing interpolation formulae for complicated problems of statistical mechanics, in which just a few terms of asymptotic expansions are available.
Baker, Baker, Benettin, Blote, Edwards, Fisher, Girardeau, Gluzman, Irving, Lieb, Muthukumar, Muthukumar, Nakamura, Oguchi, S Gluzman, Saff, Selyugin, Simon, Takahashi, Takahashi, Theodorakopoulos, V.I Yukalov, Von Meyenn, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalova, Čizek   +34 more
core   +1 more source

Book Review: Introduction to Analytical Mechanics [PDF]

, 1913
Kurt Laves
openalex   +1 more source

The CDK12–BRCA1 signaling axis mediates dinaciclib‐associated radiosensitivity through p53‐mediated cellular senescence

Molecular Oncology, Volume 19, Issue 4, Page 1265-1280, April 2025.
Dinaciclib blocks CDK12 activity, leading to downregulation of BRCA1, and probably other proteins involved in homologous recombination, promoting nonhomologous end joining. In this scenario, the presence of ionising radiation triggers a p53‐dependent senescent response that yields increased radiosensitivity. Pan‐cyclin‐dependent‐kinase (CDK) inhibitors
Natalia García Flores, Diego M. Fernández‐Aroca, Cristina Garnés‐García, Andrés Domínguez‐Calvo, Jaime Jiménez‐Suárez, Sebastià Sabater, Pablo Fernández‐Aroca, Ignacio Andrés, Francisco J. Cimas, Guillermo de Cárcer, Borja Belandia, Ignacio Palmero, Pablo Huertas, María José Ruiz‐Hidalgo, Ricardo Sánchez‐Prieto   +14 more
wiley   +1 more source