Results 121 to 130 of about 2,375,122 (290)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Geometric nonlinearities in field theory, condensed matter and analytical mechanics

open access: yesCondensed Matter Physics, 2010
There are two very important subjects in physics: Symmetry of dynamical models and nonlinearity. All really fundamental models are invariant under some particular symmetry groups.
J.J. Sławianowski
doaj   +1 more source

Lagrangian Mechanics: An Advanced Analytical Approach

open access: yes, 2019
International audienceLagrangian Mechanics explains the subtleties of analytical mechanics and its applications in rigid body mechanics. The authors demonstrate the primordial role of parameterization, which conditions the equations and thus the ...
Le Van, Anh, Bouzidi, Rabah
core   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Mechanics of materials and structures /

open access: yes, 1994
A wide range of topics in the area of mechanics of materials and structures are covered in this volume, ranging from analysis to design. There is no special emphasis on a specific area of research.
Bieniek Symposium on Mechanics of Materials and Structures(1993 :University of Virginia)   +4 more
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

An introduction to analytical mechanics

open access: yes, 2009
The present edition of this compendium is intended to be a complement to the textbook “Engineering Mechanics” by J.L. Meriam and L.G. Kraige (MK) for the course ”Mekanik F del 2” given in the first year of the Engineering physics (Teknisk fysik) programme
Cederwall, Martin,, Salomonson, Per,
core   +1 more source

Analytical elements of mechanics

open access: yes, 2013
Analytical Elements of Mechanics, Volume 1, is the first of two volumes intended for use in courses in classical mechanics. The books aim to provide students and teachers with a text consistent in content and format with the author's ideas regarding the ...
Kane, Thomas R
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

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