Results 231 to 240 of about 13,202,646 (304)

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Characterizing dynamic atmosphere generation system performance for analytical method development. [PDF]

open access: yesJ Occup Environ Hyg
Doepke A   +9 more
europepmc   +1 more source

Proceedings of the International Symposium on Analytical and Applied Pyrolysis

open access: yes, 1985
International Symposium on Analytical and Applied Pyrolysis
core  

Analytical Method Development for 19 Alkyl Halides as Potential Genotoxic Impurities by Analytical Quality by Design

open access: yesMolecules, 2022
Major issues in the pharmaceutical industry involve efficient risk management and control strategies of potential genotoxic impurities (PGIs). As a result, the development of an appropriate method to control these impurities is required.
Kyoungmin Lee
exaly   +2 more sources

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