Results 191 to 200 of about 1,060,946 (265)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Analytical Methods for the Identification of Edible and Feed Insects: Focus on DNA-Based Techniques. [PDF]

Foods
Zdeňková K, Čermáková E, Vejl P, Čermáková A, Vašek J.   +4 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Optimized Adsorption of Dyes and Antibiotics onto Natural Acacia Ataxacantha for Water Treatment

ACS Omega
Khaled Chawraba, Wassim El Malti, Assil Akil, Malak Hamieh, Mohammad Hammoud, Digambara Patra, Joumana Toufaily, Akram Hijazi   +7 more
doaj   +1 more source

Analytical methods for quantitating sulfate in plasma and serum. [PDF]

Essays Biochem
Vijayakumar P, Dawson PA.
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Review of Microchip Analytical Methods Coupled with Aptamer-Based Signal Amplification Strategies for High-Sensitivity Bioanalytical Applications. [PDF]

Biosensors (Basel)
Xue X, Hou Y, Hu C, Zhang Y.
europepmc   +1 more source

Identification of relevant analytical methods for adeno-associated virus stability assessment during formulation development. [PDF]

Microbiol Spectr
Rodenstein C, Schmid E, Markova N, Seidl A.   +3 more
europepmc   +1 more source

Analytical methods for Ir-192 determination and their comparison. [PDF]

J Radioanal Nucl Chem
Piraner O, Eardley K, Button J, Ward CD, Valentin-Blasini L.   +4 more
europepmc   +1 more source

Advancements in analytical methods for studying the human gut microbiome. [PDF]

J Biol Methods
Jansen GJ, Schouten GP, Wiersma M.
europepmc   +1 more source