Results 111 to 120 of about 1,089,942 (311)

Modeling of Zinc Dynamics in the Synaptic Cleft: Implications for Cadherin Mediated Adhesion and Synaptic Plasticity

open access: yesFrontiers in Molecular Neuroscience, 2018
While the numerous influences of synaptically released zinc on synaptic efficiency during long-term potentiation have been discussed by many authors already, we focused on the possible effect of zinc on cadherins and therefore its contribution to ...
Christoph Wolf   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Thermal Modeling of Temperature Distribution in Metal Additive Manufacturing Considering Effects of Build Layers, Latent Heat, and Temperature-Sensitivity of Material Properties

open access: yesJournal of Manufacturing and Materials Processing, 2018
A physics-based analytical model is proposed in order to predict the temperature profile during metal additive manufacturing (AM) processes, by considering the effects of temperature history in each layer, temperature-sensitivity of material properties ...
Elham Mirkoohi   +5 more
doaj   +1 more source

A practical analytic model for daylight

open access: yesProceedings of the 26th annual conference on Computer graphics and interactive techniques - SIGGRAPH '99, 1999
Sunlight and skylight are rarely rendered correctly in computer graphics. A major reason for this is high computational expense. Another is that precise atmospheric data is rarely available. We present an inexpensive analytic model that approximates full spectrum daylight for various atmospheric conditions.
A. J. Preetham   +2 more
openaire   +1 more source

Analytical solutions of the ideal model for gradient liquid chromatography

open access: yes, 2006
The analytical solutions of the ideal model for gradient elution that ignores the influence of the solute concentration on the retention factor (k) were studied by using the method of characteristics for solving partial differential equations.
Hao, Weiqiang   +2 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Analytical Model of the Two-Mass Above Resonance System of the Eccentric-Pendulum Type Vibration Table

open access: yes, 2020
The article deals with atwo-mass above resonant oscillatory system of an eccentric-pendulum type vibrating table. Based on the model of a vibrating oscillatory system with three masses, the system of differential equations of motion of oscillating masses
V.M. Borovets   +4 more
core   +1 more source

A simple analytical model to study and control azimuthal instabilities in annular combustion chambers [PDF]

open access: yes, 2012
This study describes a simple analytical method to compute the azimuthal modes appearing in annular combustion chambers and help analyzing experimental, acoustic and LES (Large Eddy Simulation) data obtained in these combustion chambers. It is based on
Wolf, Pierre   +5 more
core   +1 more source

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