Results 231 to 240 of about 26,696,093 (400)

11TH International Conference AMCM 2025. Analytical Models and New Concepts in Concrete and Masonry Structures. Abstract

Broniewicz (ed.), Miroslaw, Gryniewicz (ed.), Marcin   +1 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Analytical model for helical particle array assessment for EMI shielding applications. [PDF]

Sci Rep
Hamidi A, Cheldavi A, Habibnejad Korayem A, Baharian M.   +3 more
europepmc   +1 more source

Virtual epitexts in the dissemination of children’s books: Toward an analytical model for author websites

, 2019
Rosa Tabernero Sala, Virginia Calvo Valiós   +1 more
openalex   +1 more source

New Analytical Model for Cumulative Infiltration into Dual‐Permeability Soils

, 2014
L. Lassabatère, D. Yılmaz, X. Peyrard, P. Peyneau, Thomas Lenoir, J. Šimůnek, R. Angulo-Jaramillo   +6 more
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Analytical Model of Temperature-Induced Deformation for Tunable Thermal Expansion Metamaterial. [PDF]

Materials (Basel)
Xiao L, Yao Y, Chen S, Lai M, Zhu G.
europepmc   +1 more source

Analytic evaluation of two-loop renormalization constants of enhanced electroweak strength in the Higgs sector of the Standard Model [PDF]

, 1997
В. И. Бородулин, G. Jikia
openalex   +1 more source

A Novel Analytical Model for Flexure-based Proportion Compliant Mechanisms

, 2014
Qiaoling Meng, Yangmin Li
semanticscholar   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source