Results 141 to 150 of about 622,330 (261)

Comparative Performance of 3 Analytical Models in Identifying Associated Factors of Pulmonary Dysfunction-Depression Comorbidity: China Health and Retirement Longitudinal Study-Based Nationwide Cross-Sectional Study. [PDF]

JMIR Med Inform
Cheng Q, Cao Q, Teng W, Dai R, Jia Q, Bai X, Li Q, Wu Y, Huang Y.   +8 more
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Development of PP Compound Recipes Using Genetic Algorithms and Analytical Models. [PDF]

Polymers (Basel)
Seifert L, Leuchtenberger-Engel L, Hopmann C.   +2 more
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Salt rock creep deformation forecasting using deep neural networks and analytical models for subsurface energy storage applications. [PDF]

Sci Rep
Shukla PK, Chakraborty T, Sari M, Sarout J, Mandal PP.   +4 more
europepmc   +1 more source

Computer Simulation of Partial Discharges in Voids inside Epoxy Resins Using Three-Capacitance and Analytical Models. [PDF]

Polymers (Basel), 2020
Rodríguez-Serna JM, Albarracín-Sánchez R, Dong M, Ren M.   +3 more
europepmc   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Editorial for "Mechanical Behavior of Concrete Materials and Structures: Experimental Evidence and Analytical Models (Volume II)". [PDF]

Materials (Basel)
De Domenico D, Bernardo LFA.
europepmc   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

A systematic review of the current application status of decision-analytical models in the pharmacoeconomic evaluation of targeted therapies for pulmonary arterial hypertension. [PDF]

Cost Eff Resour Alloc
Dong W, Zhang Z, Wang X, Ma X, Chu M, Li Y, Xiang X, Peng C, Zhang R.   +8 more
europepmc   +1 more source