FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Rough Fabry–Perot cavity: a vastly multi-scale numerical problem
NanophotonicsA commercial Fabry–Perot laser diode is characterized by highly disproportionate dimensions, which poses a significant numerical challenge, even for state-of-the-art tools.
Slipchenko Tetiana +6 more
doaj +1 more source
A verified analytical sandwich beam model for soft and hard cores: comparison to existing analytical models and finite element calculations. [PDF]
Acta Mech, 2023 Schoeftner J.
europepmc +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Excess Volatility and Herding in an Artificial Financial Market: Analytical Approach and Estimation
Several agent-based models have been proposed in the economic literature to explain the key stylized facts of financial data: heteroscedasticity, fat tails of returns and long-range dependence of volatility.
Alfarano, Simone +2 more
core
Experimentally Verified Analytical Models of Piezoelectric Cantilevers in Different Design Configurations. [PDF]
Sensors (Basel), 2021 Machu Z, Rubes O, Sevecek O, Hadas Z.
europepmc +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Analytical Models in Electron Backscattering
, 1982 The different aspects of electron backscattering from solid films are calculated in terms of simple analytical models for thin films and bulk targets, for normal and oblique incidence.
Niedrig, Heinz
core
Dual-Wavelength Fluorescence Monitoring of Photodynamic Therapy: From Analytical Models to Clinical Studies. [PDF]
Cancers (Basel), 2021 Kirillin M +11 more
europepmc +1 more source
Analytical simulation modeling [PDF]
2008 Winter Simulation Conference, 2008 openaire +1 more source