Results 171 to 180 of about 703,453 (308)

How land-use-transportation models work

, 2000
This working paper serves as an introductory reference for those studying the application of landuse– transportation models to the simulation of urban systems.
Paul M. Torrens, Torrens, P.M.
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Analytical modelling of sound transmission in a lined duct

, 2013
The focus of this thesis is on the prediction of sound attenuation through a lined duct, based on a mathematical model. Ducts with a single section as well as multi-segmented sections are discussed. The duct of interest has a rectangular cross-section as
Ramli, Nabilah binti
core  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Actuarial applications of financial models. [PDF]

In the present contribution we indicate the type of situations seen from an insurance point of view, in which financial models serve as a basis for providing solutions to practical problems .
Goovaerts, Marc, Dhaene, Jan
core  

Analytical Models to Optimize Tacrolimus Dosing in Solid Organ Transplantation: A Systematic Review. [PDF]

Pharmaceutics
Amooei E, Biyani N, Buh A, Klamrowski MM, Alyahya NM, McCudden CR, Green JR, Rashidi B, Almuzirai H, Hoar S, Akbari A, Hundemer GL, Klein R.   +12 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Evaluation of analytical models to estimate depth of fluorescence objects in biological media. [PDF]

J Biomed Opt
García HA, Nguyen HM, Kwon CY, Streeter SS, Torres VC, Nguyen MH, LaRochelle EPM, Ruiz AJ, Henderson E, Davis SC, Samkoe KS.   +10 more
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Simulation or cohort models? Continuous time simulation and discretized Markov models to estimate cost-effectiveness [PDF]

The choice of model design for decision analytic models in cost-effectiveness analysis has been the subject of discussion. The current work addresses this issue by noting that, when time is to be explicitly modelled, we need to represent phenomena ...
Marta O Soares, L Canto e Castro
core