Results 61 to 70 of about 228,579 (266)

Manufacturing system sustainability through lean and agile initiatives

open access: yesInternational Journal of Sustainable Engineering, 2019
Sustainability is one of the most critical issues facing manufacturers today. The industries must develop new and innovative approaches to ensure sustainability in economic, environmental and social aspects.
Vinay Venugopal, P. G. Saleeshya
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Determine potential and social and cultural carrying capacity with the purpose of the establishment in ecotourism development (Case study: Southern Karkheh protected area, Iran) [PDF]

open access: yesتحقیقات کاربردی علوم جغرافیایی, 2022
The most important part to be considered is the determination of the carrying capacity of the protected areas, since these areas are able to accommodate a large number of tourists, so if these areas are not planned more accurately, the number of tourists
mehdi salemi, , , ,
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

HOSPITAL SITE SELECTION USING TWO-STAGE FUZZY MULTI-CRITERIA DECISION MAKING PROCESS

open access: yesJournal of Urban and Environmental Engineering, 2011
Site selection for sitting of urban activities/facilities is one of the crucial policy-related decisions taken by urban planners and policy makers. The process of site selection is inherently complicated.
Ali Soltani, Ebrahim Zargari Marandi
doaj   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

MODEL ANALYTICAL NETWORK PROCESS (ANP) DALAM PENGEMBANGAN PARIWISATA DI JEMBER

open access: yesJurnal Economia, 2015
Abstrak    : Model Analytical Network Process (ANP) dalam Pengembangan Pariwisata di Jember. Penelitian ini mengkaji kebijakan pengembangan pariwisata di Jember, terutama kebijakan pengembangan agrowisata perkebunan kopi dengan menggunakan Jember Fashion
Sukidin Sukidin, Pudjo Suharso
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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