Results 61 to 70 of about 529 (166)

Model inversion and three-way decompositions in the analytical quality by design strategy for the determination of phthalates BY HS-SPME-GC-MS [PDF]

In this work, strategies within Analytical Quality by Design (AQbD) with tools of the Process Analytical Technology (PAT) were used in the development of a head space-solid phase microextraction-gas chromatography-mass spectrometry (HS-SPME-GC-MS ...
Herrero Gutiérrez, Ana, Ortiz Fernández, Mª Cruz, Reguera Alonso, Celia, Sarabia Peinador, Luis Antonio, Sánchez Pastor, Mª Sagrario, Valverde Som, Lucía   +5 more
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Analytical quality by design (AQbD) assisted RP-HPLC technique for quantification of Picroside II in bulk and pharmaceutical dosage form

Future Journal of Pharmaceutical Sciences
Abstract Background Quality by design (QbD) adverts toward gaining of few expected quality with predetermined and desired specifications. Analytical quality by design (AQbD) approach toward the development of analytical method can significantly lead toward the rugged and robust method specially the assessment and risk
Sharib Raza Khan, Shailesh Dadge, Shivam Rathaur, Jiaur R. Gayen   +3 more
openaire   +2 more sources

OPTIMASI DAN VALIDASI METODE KLT-DENSITOMETRI PADA ANALISIS FARMASI : TINJAUAN KRITIS DAN STUDI KOMPARATIF [PDF]

Kromatografi Lapis Tipis (KLT) Densitometri atau High Performance Thin Layer Chromatography (HPTLC) tetap menjadi metode analisis instrumental yang vital, terutama di negara berkembang, karena efisiensi biaya dan kemampuannya menangani banyak sampel ...
Anggrainy, Dian Sari, Chantika, Shelfia Putri, Fadhilah, Fauzi Rizki, Marfanie, Auryn Difani, Nugraha, Nadia Afianti, Putra, Muqsidana Sayidina Gara, Sinaga, Jessica Putri   +6 more
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ANALYTICAL QUALITY-BY-DESIGN (AQBD) APPROACH FOR THE DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR THE ESTIMATION OF LAMOTRIGINE IN BULK AND TABLET FORMULATION

Journal of Medical pharmaceutical and allied sciences, 2021
The current analytical exploration illustrated developing a reversed-phase high-performance liquid chromatography (RP-HPLC) technique and consequent substantiation for analyzing lamotrigine (LAM) active pharmaceutical ingredient (API) using a Quality-by-design (QbD) approach (Central Composite Design), in bulk product as well as in the tablet ...
openaire   +1 more source

Application of Qbd Principles to Develop and Validate a Method for Cinacalcet Determination in Api and Its Dosage Form [PDF]

Introduction: Cinacalcet Hcl [CIN] is used to treat hyperthyroidism and hypercalcisim. and improves the sensitivity of calcium receptors on parathyroid cells to reduce parathyroid harmone levels and hence decrease serum calcium levels. It also has a role
A.Srinija, Sneha Takur, R.Prasanthi, Buggana Siva Jyothi, R.Swetha Sri
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Application of Analytical Quality by Design (AQbD) in Developing Robust Methods for Herbicide Analysis-A Case Study on Metribuzin

International Journal of Pharmaceutical Research and Applications
Analytical Quality by Design (AQbD) applies Quality by Design principles to analytical method development, aiming to design methods that are robust, well-understood, and life cycle managed. Herbicide residue analysis (monitoring active compounds and metabolites in formulations, food, soil, and water) presents challenges of trace-level detection, matrix
Wafa T Wafa T, Shifa Mammed Kutty K M, Saranya Mohan, Najah P A Meena P V   +3 more
openaire   +1 more source

Aplicação do princípio "Analytical Quality by Design (AQbD) no desenvolvimento do método indicativo de estabilidade para oclacitinibe [PDF]

, 2021
Orientador: Prof. Dr. Roberto PontaroloDissertação (mestrado) - Universidade Federal do Paraná, Setor de Ciências da Saúde, Programa de Pós-Graduação em Ciências Farmacêuticas. Defesa : Curitiba, 28/05/2021Inclui referências: p.
Momade, Danilo Raul Ossufo, 1989-
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Analytical quality by design (AQbD) based optimization of RP-UPLC method for determination of nivolumab and relatlimab in bulk and pharmaceutical dosage forms

Future Journal of Pharmaceutical Sciences
Abstract Background The Analytical Quality by Design (AQbD) methodology extends the application of Quality by Design (QbD) principles to the management of the analytical procedure life cycle, encompassing method creation, optimization, validation, and continuous improvement. AQbD assists in creating analytical procedures
Mohana Vamsi Nuli, Ramanjaneyulu Seemaladinne, Anil Kumar Tallam   +2 more
openaire   +2 more sources

Design Approach in RP-HPLC Method Development and Validation of Nirogacestat in its Pure and Pharmaceutical Dosage Form [PDF]

Aim: Nirogacestat is a selective γ-secretase inhibitor approved by the USFDA for the treatment of Desmoid Tumour. Objective: In this study, a reversed-phase high performance liquid chromatography (RP-HPLC) method was designed to analyze the concentration
Chandrasekar R, Sivagami B, Roshini M, Kumanan R, Sudha S, Sai Koteswar Sharma
core   +1 more source

Protein corona characterization through analytical quality-by-design [PDF]

, 2019
Présentation PosterNational audienceAfter administration of nanoparticles (NP) into biological fluids, the NP may interact with surrounding biomolecules like proteins.
Bastogne, Thierry, Deleforterie, Jeanne
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