Results 91 to 100 of about 2,120,758 (270)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Pharmacological and analytical aspects of artemisinin for malaria: Advances and challenges
Asian Pacific Journal of Tropical Medicine, 2019 Malaria remains a major tropical health burden owing to the development of resistance and decreased sensitivity to the frequently used conventional antimalarial drugs.
Sravani Karri +2 more
doaj +1 more source
THE USE OF ANALYTICAL PROCEDURES IN AFFILIATED AND NON-AFFILIATED AUDIT FIRMS [PDF]
, 2017 The aim of the research was to investigate the allocated time and the frequency of the use of analytical procedures in affiliated and non-affiliated audit firms, and to examine the frequency the effectiveness of various types of analytical techniques by ...
HARTO, Puji, SITI, Aisyah Fitria
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
MathematicsNew types of truncated M-fractional wave solitons to the simplified Modified Camassa–Holm model, a mathematical physics model, are obtained. This model is used to explain the unidirectional propagation of shallow water waves.
Abdulrahman Alomair +2 more
doaj +1 more source
A wind-tunnel evaluation of analytical techniques for predicting static stability and control characteristics of flexible aircraft [PDF]
An experimental evaluation of analytical techniques for predicting certain stability and control characteristics of a large flexible aircraft is presented.
Abel, I.
core +1 more source
Bias Reduction of Long Memory Parameter Estimators via the Pre-filtered Sieve Bootstrap [PDF]
, 2014 This paper investigates the use of bootstrap-based bias correction of semi-parametric estimators of the long memory parameter in fractionally integrated processes.
Grose, Simone D. +2 more
core
, 2012 We investigate one of the most common analytic continuation techniques in condensed matter physics, namely the Pad\'{e} approximant. Aspects concerning its implementation in the exact muffin-tin orbitals (EMTO) method are scrutinized with special regard ...
Chioncel, L., Vitos, L., Östlin, A.
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source