Results 81 to 90 of about 7,257,540 (295)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Metabolomics of Solanum lycopersicum Infected with Phytophthora infestans Leads to Early Detection of Late Blight in Asymptomatic Plants

Molecules, 2018
Tomato crops suffer attacks of various pathogens that cause large production losses. Late blight caused by Phytophthora infestans is a devastating disease in tomatoes because of its difficultly to control.
Paula Galeano Garcia, Fábio Neves dos Santos, Samantha Zanotta, Marcos Nogueira Eberlin, Chiara Carazzone   +4 more
doaj   +1 more source

The Journal of analytical and applied chemistry.

, 1891
Edited by: Edward Hart.Title from cover.Contains "A bibliography of analytical chemistry ... 1866-92," by H.C.
Hart, Edward, 1854-, Bolton, H. C. Bibliography of analytical chemistry.   +1 more
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Mass spectrometry analysis of change of phospholipids in biological membrane by external environmental effects

, 1998
2
장윤석
core  

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The role of selenium in mercury toxicity: current analytical techniques and future trends in analysis of selenium and mercury interactions in biological matrices

, 2017
Mercury forms potent toxic compounds, which cause irreversible damage to the central nervous system, while selenium, if present in an adequate concentration, is an essential micronutrient needed for the regulation of metabolic processes. The interactions
Mester, Zoltan, Gajdosechova, Zuzana, Jörg Feldmann, Zoltan Mester, Eva M. Krupp, Krupp, Eva M., Zuzana Gajdosechova, Feldmann, J\uf6rg, Feldmann, Jörg   +8 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Controlling Surface-Induced Platelet Activation by Agarose and Gelatin-Based Hydrogel Films

ACS Omega, 2021
Gurunath Apte, Annerose Lindenbauer, Jörg Schemberg, Holger Rothe, Thi-Huong Nguyen   +4 more
doaj   +1 more source

Transdisciplinary Studies for Valorisation of National Cultural Heritage Using Nuclear Techniques and Other Associated Methods

Digital Presentation and Preservation of Cultural and Scientific Heritage, 2018
The presented project aims to offer integrated methodologies for the valorisation of national cultural heritage using nuclear and other analytical techniques.
Radu Claudiu Fierascu, Irina Fierascu, Valentin Raditoiu, Cristian-Andi Nicolae, Mihnea Dulea, Dragos Alexandru Mirea   +5 more
doaj   +1 more source