Results 91 to 100 of about 7,257,540 (295)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

New Abundant Analytical Solitons to the Fractional Mathematical Physics Model via Three Distinct Schemes

Mathematics
New types of truncated M-fractional wave solitons to the simplified Modified Camassa–Holm model, a mathematical physics model, are obtained. This model is used to explain the unidirectional propagation of shallow water waves.
Abdulrahman Alomair, Abdulaziz S. Al Naim, Ahmet Bekir   +2 more
doaj   +1 more source

OPTIMIZATION OF GAS-CHROMATOGRAPHIC ANALYTICAL METHODS FOR TOXIC COMPOUNDS IN AIR

, 1994
This is a review article concernning the development of a gas chromatographic analytical method for the analysis of 70 air toxic compounds. Not only the operating conditions, but also the column system is optimized.
LU, PC, LI, Y, ZHANG, XM, XU, GW, ZHANG, YK   +4 more
core  

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Concentration of polycyclic aromatic hydrocarbons in roasted coffee beans: a systematic review

Beverage Plant Research
Coffee is one of the most popular beverages worldwide, and its consumption continues to rise. Coffee beans can be sold as roasted coffee or as green beans.
Kiandokht Ghanati, Behrouz Akbari-Adergani, Namra Irshad, Bahare Mohamadi, Amirhossein Abedini, Parisa Shavali-gilani, Parisa Sadighara   +6 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Impact of Microplastics on Human Health: A Comprehensive Review

Journal of Preventive, Diagnostic and Treatment Strategies in Medicine
This comprehensive review explores microplastic (MP) contamination in food and Incorporating nanotechnology into food packaging. It covers origins, pathways, health consequences, and analytical challenges. Microplastics (MPs), which are generation due to
R. Prathipa, Niranjana Karukayil Gopalakrishnan, Aditi Chaudhary, Manikantan Pappuswamy   +3 more
doaj   +1 more source

Process Analytical Techniques Based on In-Line Vibrational Spectroscopy and their Industrial Applications [PDF]

Kemija u Industriji, 2013
Process analytical techniques (PAT) involve the monitoring and control of physical and chemical processes as well as the identification of important process parameters in order to obtain the products with desired properties.
Jednačak, T., Novak, P.
doaj