Results 141 to 150 of about 60,111 (283)

Dual Inhibition of Mast Cells and Thymic Stromal Lymphopoietin Using a Novel Bispecific Antibody, CDX‐622

open access: yesAllergy, EarlyView.
SCF and TSLP expression are known to drive unique immune responses leading to the onset of allergic and inflammatory diseases. Here, we describe the characterization of a novel bsAb, CDX‐622, that targets SCF and TSLP. CDX‐622 inhibits MC functions through SCF starvation and Type 2 inflammatory responses via TSLP inhibition.
Michael B. Murphy   +17 more
wiley   +1 more source

Current use of push‐dose epinephrine: Survey and interview results from academic clinicians in emergency medicine

open access: yes
Academic Emergency Medicine, EarlyView.
Andrew K. Posen   +3 more
wiley   +1 more source

Non‐Allergic Urticarial Skin Reactions Associated With MOv18 IgE, a First‐In‐Class IgE Antibody Recognising Folate Receptor Alpha

open access: yesAllergy, EarlyView.
MOv18 IgE, the first‐in‐class IgE antibody targeting the cancer antigen folate receptor alpha (FR⍺) showed early signs of efficacy and was well tolerated in a first‐in‐human clinical trial, with transient urticarial skin reactions as the most common toxicity.
Chara Stavraka   +28 more
wiley   +1 more source

Vaccine‐Induced Anti‐IgE Antibodies Neutralize Free IgE but Fail to Bind and Activate Mast Cell‐Displayed IgE

open access: yesAllergy, EarlyView.
We investigated the mechanisms by which a previously established VLP‐based anti‐IgE vaccine protects against allergic anaphylaxis. We show that passively administered vaccine‐induced IgGs into allergic mice protects them from anaphylaxis without side effects.
Zahra Gharailoo   +3 more
wiley   +1 more source

VI. —Anaphylaxis and anaphylatoxins

open access: gold, 1923
H. H. Dale, Charles H. Kellaway
openalex   +1 more source

Anaphylaxis in outpatients: A 5‐year retrospective study on incidence and clinical characteristics at a university hospital in Wuhan, China

open access: yes
Allergy, EarlyView.
Le Li   +7 more
wiley   +1 more source

Immunological In Vitro Assay for Quantification of Adjuvanted Allergoids

open access: yesAllergy, EarlyView.
An assay was developed to measure the allergoid content in adjuvanted grass allergoid AIT drug product (AIT‐DPs) at the finished product level. Both polyclonal rabbit sera or a mouse anti‐Phl p 5 mAb can be used, allowing differential product analysis.
S. Schlünder   +5 more
wiley   +1 more source

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