Results 141 to 150 of about 60,111 (283)
SCF and TSLP expression are known to drive unique immune responses leading to the onset of allergic and inflammatory diseases. Here, we describe the characterization of a novel bsAb, CDX‐622, that targets SCF and TSLP. CDX‐622 inhibits MC functions through SCF starvation and Type 2 inflammatory responses via TSLP inhibition.
Michael B. Murphy+17 more
wiley +1 more source
THE SIGNIFICANCE OF ANAPHYLAXIS IN PNEUMOCOCCUS IMMUNITY [PDF]
G. M. Mackenzie
openalex +1 more source
MOv18 IgE, the first‐in‐class IgE antibody targeting the cancer antigen folate receptor alpha (FR⍺) showed early signs of efficacy and was well tolerated in a first‐in‐human clinical trial, with transient urticarial skin reactions as the most common toxicity.
Chara Stavraka+28 more
wiley +1 more source
We investigated the mechanisms by which a previously established VLP‐based anti‐IgE vaccine protects against allergic anaphylaxis. We show that passively administered vaccine‐induced IgGs into allergic mice protects them from anaphylaxis without side effects.
Zahra Gharailoo+3 more
wiley +1 more source
TRANSMISSION OF RESPIRATORY ANAPHYLAXIS (ASTHMA) FROM MOTHER TO OFFSPRING [PDF]
Bret Ratner, Helen Lee Gruehl
openalex +1 more source
Immunological In Vitro Assay for Quantification of Adjuvanted Allergoids
An assay was developed to measure the allergoid content in adjuvanted grass allergoid AIT drug product (AIT‐DPs) at the finished product level. Both polyclonal rabbit sera or a mouse anti‐Phl p 5 mAb can be used, allowing differential product analysis.
S. Schlünder+5 more
wiley +1 more source