Results 161 to 170 of about 64,244 (297)

Reducing or Eliminating Polysorbate Induced Anaphylaxis and Unwanted Immunogenicity in Biotherapeutics – Review Article [PDF]

The increasing use of biotherapeutics across a growing spectrum of neoplastic, autoimmune, and inflammatory diseases has resulted in a corresponding increase in hypersensitivity reactions.
Edward Maggio
core  

Determinants of Poor Health‐Related Quality of Life in Patients With Food Allergy

Allergy, EarlyView.
Machine‐learning analysis of 502 well‐characterised food‐allergic patients was used to identify key determinants of poor FA‐HRQL, defined as FAQLQ ≥ 5. The most relevant predictors were adult age, female sex, multiple food allergies, severe reactions, need for urgent care, onset before 18 years, and longer disease duration.
Rosialzira Natasha Vera‐Berrios, Alejandro Gonzalo‐Fernández, Natalia Freundt‐Serpa, Guadalupe Marco‐Martín, Beatriz Fernández‐Parra, María Isabel Alvarado‐Izquierdo, Rocío Casas‐Saucedo, Cristina Stein‐Coronado, Ethel Ibáñez‐Echevarría, Tania Ramos‐García, María Dolores Alonso‐Díaz de Durana, Azahara López‐Raigada, Carlos Blanco‐Guerra, María Pía de Calzada‐Bustingorri, Teresa Carrillo‐Díaz, Hilda Rianec Hernández‐Suárez, Miguel Ángel Díaz‐Palacios, Sonsoles Infante‐Herrero, Ana María Nieto‐Nieto, Sonia Vázquez‐Cortés, Eloína González‐Mancebo, María M. Escribese, Pilar Rico‐Nieto, Domingo Barber, Montserrat Fernández‐Rivas   +24 more
wiley   +1 more source

International Pain and Spine Intervention Society emergency protocols: Allergic and anaphylactic reactions. [PDF]

Interv Pain Med
Smith CC, Meral RM, Wasserman RA.
europepmc   +1 more source

Diet–Microbiome–Immune Interactions at the Gut Mucosa in Food Allergy: Mechanisms, Gaps, and Therapeutic Implications

Allergy, EarlyView.
ABSTRACT Mucosal surfaces are sites of highly dynamic interactions among epithelial and immune cells, environmental exposures, particularly dietary inputs, and the diverse microbial communities and their metabolites. These elements continually influence each other to maintain homeostasis and ensure appropriate immune discrimination between pathogens ...
Clara Delaroque, Liam O'Mahony, Inge Kortekaas Krohn, Charlotte G. Mortz, Markus Ollert, Mahesh S. Desai   +5 more
wiley   +1 more source

Evaluation of anaphylactic reactions involving carboplatin and paclitaxel reported to the FDA from 1970 to 2023. [PDF]

Gynecol Oncol Rep
Petrie H, Boucher T, Crispens MA, Phillips EJ, Stone CA.   +4 more
europepmc   +1 more source

Global Variation in Timing of Allergenic Food Introduction for Food Allergy Prevention: An International Survey of Healthcare Professionals

Allergy, EarlyView.
This study examines the current state of food allergy prevention guideline implementation worldwide, identifying key variables that may explain the observed global variation. Among 731 healthcare professionals across 80 countries, geography and clinical specialty independently drove allergenic food introduction practices, creating an 8.5‐month practice
Agnes Sze‐yin Leung, Elizabeth Huiwen Tham, Kiwako Yamamoto‐Hanada, Derek K. Chu, Matthew Norris, Daria Levina, Daniel Munblit, Lamia Dahdah, Luciana Kase Tanno, Carmen Riggioni, Elsy M. Navarrete‐Rodriguez, Michael E. Levin, Thulja Trikamjee, William Guo, Chun Tong Lei, Chun Pong Lau, Supinda Bunyavanich, Nikolaos G. Papadopoulos, Adnan Custovic, Christina West, Gary Wing‐kin Wong   +20 more
wiley   +1 more source

Development of a Clinical Prediction Model for Recurrent Anaphylaxis. [PDF]

J Clin Med
Uthaisangsook S, Inkate S, Wangchiraniran S.   +2 more
europepmc   +1 more source

Time‐Resolved Multi‐Omics Identify Biomarkers of Immediate Reactions to mRNA Vaccination

Allergy, EarlyView.
We compared early vaccine‐induced immune and metabolic signatures and downstream immunity after second and booster BNT162b2 doses in participants with sARs, ISSRs, or no reactions. Neutrophil mobilization, antiviral programs, and robust anti‐S‐antibody responses occurred across reaction groups.
Ana Olivera, Benjamin Schwarz, Brittany Dulek, Ian S. LaCroix, Min Li, Lindsay Chatman, Muhammad B. Khalid, Ellen Zektser, Karen Laky, Stella Hartono, Eric Bohrnsen, Cole D. Kimzey, Eric Chu, Roa Harb, Pamela A. Frischmeyer‐Guerrerio   +14 more
wiley   +1 more source

Recombinant human diamine oxidase prevents histamine-induced hypoxia, shock and death in guinea pigs. [PDF]

Inflamm Res
Kosta F, Weiss-Tessbach M, Gludovacz E, Reiter B, Murauer M, Jilma B, Rager-Resch M.   +6 more
europepmc   +1 more source

Basophils in Immunity: Activation Pathways, Roles in Allergy and AllergoOncology and Application of the Basophil Activation Test

Allergy, EarlyView.
ABSTRACT Basophils, the least abundant leukocytes, are increasingly recognised as potent immunomodulators. Upon activation, they rapidly release preformed granule‐associated mediators including histamine and lipid mediators such as LTC4, while cytokine production occurs over a longer timescale, contributing to downstream immune responses.
Jitesh Chauhan, Sofia Vlasova, Alicia Chenoweth, Debra H. Josephs, Heather J. Bax, Sophia N. Karagiannis   +5 more
wiley   +1 more source