Abstract Background Limited real‐world data exist on recombinant fusion protein‐linking coagulation factor IX (FIX) with albumin (rIX‐FP) in paediatric previously untreated patients (PUPs) with haemophilia B, particularly in infants. Aims To evaluate the treatment patterns, safety and efficacy of rIX‐FP in paediatric PUPs in Japan.
Keiji Nogami +3 more
wiley +1 more source
Severe anaphylaxis following off-label rectal use of injectable diazepam in a febrile seizure: a case report and clinical implications. [PDF]
Nguyen NX +6 more
europepmc +1 more source
Anaphylaxis
Dimitry Buyansky +12 more
openalex +1 more source
ABSTRACT Background Synthetic dialysis membranes, particularly those composed of polysulfone blended with polyvinylpyrrolidone, are commonly used in hemodialysis due to their efficiency. However, hypersensitivity reactions—often atypical and not fitting traditional type A and B classifications—have increasingly been reported.
Víctor Joaquín Escudero‐Saiz +9 more
wiley +1 more source
Insights Into Complex Murine Models of Allergy and Anaphylaxis: The Central Role of IgE and Mast Cells in Advancing Human Therapies. [PDF]
Nagata Y, Suzuki R.
europepmc +1 more source
First successful protocol for desensitization to eptinezumab
Abstract Background Eptinezumab is an anti‐calcitonin gene‐related peptide monoclonal antibody used for migraine prevention. During clinical trials, hypersensitivity to eptinezumab was described without a clear underlying mechanism. To determine if the reaction was immunoglobulin E–mediated, the team of Nice University Hospital (Nice, France) performed
Benoit Gerard +8 more
wiley +1 more source
A reference centre experience in central Anatolia in terms of causes, severity and treatment of childhood anaphylaxis. [PDF]
Guzel T +3 more
europepmc +1 more source
Safety and efficacy of nemolizumab for atopic dermatitis up to 2 years in open‐label extension study
This study evaluated long‐term safety and efficacy in patients with moderate‐to‐severe atopic dermatitis. Patients with and without previous nemolizumab experience received nemolizumab 30 mg Q4W plus TCS/TCI. Nemolizumab was well‐tolerated through 104 weeks with clinically meaningful improvements in disease signs and symptoms.
Matthias Augustin +24 more
wiley +1 more source
Severe anaphylactic reaction to contrast agent: teams are well prepared but should simulate the situations regularly. [PDF]
Pape KC +18 more
europepmc +1 more source

