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Anaphylaxis is an acute, potentially fatal systemic reaction with varied mechanisms and clinical presentations. Although prompt recognition and treatment of anaphylaxis are imperative, both patients and healthcare professionals often fail to recognize and diagnose early signs and symptoms of the condition.
Kim, Harold, Fischer, David
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Does treatment with antidepressants, antipsychotics, or benzodiazepines hamper allergy skin testing?
Background Treatment with commonly used drugs such as antidepressants (ADs), antipsychotics (APs), and benzodiazepines (BDs) may hamper the use of allergy skin testing due to possible antihistaminic effects. Objective To examine the antihistaminic effect
Henrik Fomsgaard Kjaer+2 more
doaj +1 more source
The role of PAF in immunopathology: From immediate hypersensitivity reactions to fungal defense
Abstract Platelet‐activating factor (PAF, 1‐alkyl‐2‐acetyl‐sn‐glycero‐3‐phosphorylcholine) was discovered when the mechanisms involved in the deposition of immune complex in tissues were being scrutinized in the experimental model of rabbit serum sickness.
Mariano Sánchez Crespo+2 more
wiley +1 more source
Background During the COVID‐19 pandemic focus has been on polyethylene glycol (PEG) and polysorbate as these excipients are constituents in the first vaccines and possible elicitors of allergic reactions to the vaccines.
Charlotte G. Mortz+5 more
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Carboxymethylcellulose (CMC, carmellose sodium) is an anionic water‐soluble polymer derived from native cellulose that is used as an excipient. Here, we report a case of urticaria caused by the CMC in lidocaine jelly and dimethicone drops. Abstract Excipient allergies are rare and difficult to diagnose.
Eri Hotta+9 more
wiley +1 more source
Diagnosis and treatment trilogy for anaphylaxis in children [PDF]
Anaphylaxis is an acute presentation of systemic allergic reactions which may lead to death without improper diagnosis and treatment. Children are the high-risk population of anaphylaxis, and the incidence of anaphylaxis tends to increase.
Yang Lifen, Yang Kexin, Kong Qian, Chen Zhuanggui
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Autosomal recessive hyper‐IgE syndrome due to DOCK8 deficiency: An adjunctive role for omalizumab
We report a rare case of AR‐HIES with DOCK8 deficiency in a young male that was successfully treated by infection management, skincare, diet elimination, and omalizumab. Abstract Autosomal recessive hyper‐IgE syndrome (AR‐HIES) is a rare primary immunodeficiency disorder characterized by high serum IgE levels, recurrent viral skin infections, severe ...
Kim Han Nguyen+8 more
wiley +1 more source
Our previous studies indicated that ultrasound treatment can increase the anaphylaxis of protein. However, investigation on the anaphylaxis changes of ultrasound-treated α-lactalbumin (ALA) during digestion is lacking.
Xumei Wang+5 more
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Nasal symptoms in patients with NSAID hypersensitivity [PDF]
Background: Approximately 1 to 2% of the general population suffers from nonsteroidal anti-inflammatory drugs (NSAID) hypersensitivity. NSAID hypersensitivity is closely associated with concomitant respiratory disease.
B. Lange+3 more
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The clinical syndrome of anaphylactic shock is a disorder produced by multiple mechanisms and pharmacological and environmental factors. The syndrome may be produced by both immunologic and nonimmunologic mechanisms and is due to the release of preformed biologically active mediators and the generation of biologically active mediators.
openaire +4 more sources