The biological activity of soluble antigen-antibody complexes: II. Physical properties of soluble complexes having skin-irritating activity [PDF]
, 1959 Previous work by Germuth and McKinnon (1), Trapani et al. (2), and ourselves (3) has established the fact that soluble antigen-antibody complexes formed in excess antigen can, (a) induce symptoms similar to anaphylaxis, (b) cause contraction of isolated ...
Campbell, Dan H. +2 more
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Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management
Advanced Science, EarlyView.ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak +9 more
wiley +1 more source
Association of immune response with efficacy and safety outcomes in adults with phenylketonuria administered pegvaliase in phase 3 clinical trials [PDF]
, 2018 Background: This study assessed the immunogenicity of pegvaliase (recombinant Anabaena variabilis phenylalanine [Phe] ammonia lyase [PAL] conjugated with polyethylene glycol [PEG]) treatment in adults with phenylketonuria (PKU) and its impact on safety ...
Atkinson, John P +14 more
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Anaesthesia, 1984 The clinical syndrome of anaphylactic shock is a disorder produced by multiple mechanisms and pharmacological and environmental factors. The syndrome may be produced by both immunologic and nonimmunologic mechanisms and is due to the release of preformed biologically active mediators and the generation of biologically active mediators.
openaire +4 more sources
Advanced Science, EarlyView.ABSTRACT Platelet transfusions to treat bleeding complications use donor‐derived platelets stored at room‐temperature, that have a shelf‐life of only 5–7 days due to bacterial contamination risks. Cold‐stored and freeze‐dried platelets are being investigated for extending shelf‐life, but these still have the inherent challenge of donor‐dependency.
Ujjal Didar Singh Sekhon +20 more
wiley +1 more source
Different clinical features of anaphylaxis according to cause and risk factors for severe reactions
Allergology International, 2018 Background: Anaphylaxis is a life-threatening allergic reaction. Several studies reported different anaphylactic reactions according to the causative substances. However, a comparison of anaphylaxis for each cause has not been done.
Sang-Yoon Kim +2 more
doaj +1 more source
Treatment of Anaphylaxis in Adults: A Questionnaire Survey [PDF]
, 2009 Objective: To identify the medications that medical students, interns and casualty medical officers are likely to prescribe when treating an adult patient with anaphylaxis, and to ascertain the dose and route of administration of adrenaline they would ...
Adiga, Shalini, Bairy, KL, Nayak, Veena
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Cross-sensitization between poppy seed and buckwheat in a food-allergic patient with poppy seed anaphylaxis [PDF]
, 2006 The opium poppy, Papaver somniferum L., is the source of both poppy seeds and opium. The commercially available seeds are widely used as ingredients for various kinds of food.
Oppel, T., Thomas, P., Wollenberg, A.
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Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles
Advanced Science, EarlyView.Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu +6 more
wiley +1 more source
CAQ Corner: Basic concepts of transplant immunology
, 2022 Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
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