Results 51 to 60 of about 64,042 (297)

Timing of onset of intraoperative transfusion anaphylaxis: a literature review [PDF]

open access: yes
Clinical diagnosis of intraoperative transfusion anaphylaxis using clinical symptoms is challenging and should be made carefully, as an incorrect clinical diagnosis can exacerbate surgical bleeding secondary to stopping a clinically indicated blood ...
Hirai, Takahiro   +4 more
core   +1 more source

Efficacy and Safety of Guselkumab in Participants With Active Psoriatic Arthritis After Inadequate Response to One Prior Tumor Necrosis Factor Inhibitor: Week‐24 Results of a Phase 3, Randomized, Placebo‐Controlled Study

open access: yesArthritis &Rheumatology, EarlyView.
Objective To evaluate the efficacy and safety of guselkumab, an interleukin‐23p19 subunit inhibitor, in participants with active psoriatic arthritis (PsA) and inadequate response (inadequate efficacy and/or intolerance) to one prior tumor necrosis factor (TNF) inhibitor.
Alexis Ogdie   +12 more
wiley   +1 more source

Education Is Key! Call for Action!

open access: yesEuropean Medical Journal Allergy & Immunology, 2017
I have been asked to share my opinion about the diagnostics of anaphylaxis and how to treat it. As you probably know, anaphylaxis is the extreme outing of an allergic reaction and is likely if any one of three criteria is fulfilled (Figure 1).1 Assessing
Frans Timmermans
doaj  

Emergency anaphylaxis protocols: A cross-sectional analysis of general practice surgeries and pharmacies in both the urban and rural setting in Ireland

open access: yesEuropean Journal of General Practice, 2018
Background: The incidence of anaphylaxis appears to be increasing worldwide with cases in the community outnumbering those in the hospital setting. General practice (GP) surgeries and pharmacies, based in the community, are often the first point of ...
Hannah O’Brien   +3 more
doaj   +1 more source

Anaphylaxis [PDF]

open access: yesAnaesthesia, 1984
The clinical syndrome of anaphylactic shock is a disorder produced by multiple mechanisms and pharmacological and environmental factors. The syndrome may be produced by both immunologic and nonimmunologic mechanisms and is due to the release of preformed biologically active mediators and the generation of biologically active mediators.
openaire   +4 more sources

Navigating adverse immunostimulation: A practical guide for clinical researchers

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort   +3 more
wiley   +1 more source

Comparison of anaphylaxis epidemiology between urban and suburban pediatric emergency departments

open access: yesBMC Pediatrics, 2023
Background Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death. To date, there are no published data on epidemiology of pediatric anaphylaxis in Michigan.
Dhritiman Gurkha   +3 more
doaj   +1 more source

Efficacy and safety of empagliflozin for treating neutropenia and neutrophil dysfunction in paediatric patients with glycogen storage disease type Ib: A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk   +5 more
wiley   +1 more source

A multicenter anaphylaxis registry in Korea: Clinical characteristics and acute treatment details from infants to older adults

open access: yesWorld Allergy Organization Journal, 2020
Background: Although the prevalence of anaphylaxis is increasing worldwide, the large-scale studies in Asia evaluating anaphylaxis in all age groups are limited.
Kyunguk Jeong   +29 more
doaj   +1 more source

Does anaphylaxis masquerade as asthma in children?

open access: yes, 2015
Anaphylaxis in children presents most frequently with respiratory features, and concern exists about the potential for diagnostic confusion with acute asthma. 84 cases of asthma requiring intensive care were identified.
Erlewyn-Lajeunesse, M.   +4 more
core   +1 more source

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