Results 71 to 80 of about 70,282 (294)

Engineering mRNA‐LNP Medicines for the Ageing Brain: Opportunities and Challenges for Neurodegenerative Diseases

Exploration, EarlyView.
This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi, Denzil L. Furtado, Francesca Alves, Rebecca M. Nisbet, Scott Ayton, Ashley I. Bush   +5 more
wiley   +1 more source

An IgG-induced neutrophil activation pathway contributes to human drug-induced anaphylaxis [PDF]

, 2019
International audienceAnaphylaxis is a systemic acute hypersensitivity reaction that is considered to depend on allergen-specific immunoglobulin E (IgE) antibodies and histamine release by mast cells and basophils.
Gouel-Chéron, A, Bay, Sylvie, Tubach, F, Christelle Ganneau, Plaud, Benoît, Longrois, D, Guinnepain, M-T, Bruhns, P, Cholley, B, Bay, S, Guinnepain, Marie-Therese, Aubier, M, Caitlin M. Gillis, Matthieu Le Dorze, Sylvie Bay, Zhu, Q, Granger, V, Cholley, Bernard, Plaud, B, Marc Fischler, Longrois, Dan, Paugam-Burtz, C, Zhu, Qianqian, Hawa Keita-Meyer, Fischler, M, Dan Longrois, De Chaisemartin, Luc, Gouel-Chéron, Aurélie, Langeron, O, Hurtado-Nedelec, Maria, Luc de Chaisemartin, Dib, F, Caroline Sauvan, Gillis, Caitlin, Dib, Fadia, Catherine Neukirch, Montravers, P, Maria Hurtado-Nedelec, Skander Necib, Gillis, CM, Sylvie Chollet-Martin, Jacob, L, Bernard Cholley, Philippe Montravers, Pierre Bruhns, Olivier Langeron, Tubach, Florence, Granger, Vanessa, Qianqian Zhu, Jönsson, F, Ganneau, Christelle, Montravers, Philippe, Laurent Jacob, Paugam-Burtz, Catherine, Le Dorze, Matthieu, Chollet-Martin, Sylvie, Jönsson, Friederike, Aubier, Michel, Jacob, Laurent, Le Dorze, M, Fischler, Marc, Neukirch, C, Nicaise-Roland, Pascale, Marie-Thérèse Guinnepain, Bruhns, Pierre, de Chaisemartin, L, Florence Tubach, Neukirch, Catherine, Friederike Jönsson, Necib, Skander, Langeron, Olivier, Keita-Meyer, H, Vanessa Granger, Benoit Plaud, Hurtado-Nedelec, M, Aurélie Gouel-Chéron, Sauvan, Caroline, Pascale Nicaise-Roland, Necib, S, Nicaise-Roland, P, Ganneau, C, Sauvan, C, Fadia Dib, Catherine Paugam-Burtz, Keita-Meyer, Hawa, Chollet-Martin, S, Michel Aubier   +86 more
core   +1 more source

“Effects of High‐Intensity Ultrasound on the Structural, Technofunctional, and Allergenic Properties of Groundnut (Arachis hypogaea L.) Protein Isolates: A Review”

Food Chemistry International, EarlyView.
ABSTRACT The growing global demand for sustainable, nutritionally balanced protein sources has intensified interest in plant‐derived proteins, particularly those derived from oilseeds such as groundnut (Arachis hypogaea L.). However, although groundnut protein isolates (GPIs) have high nutritional quality, they exhibit limitations in technofunctional ...
Ángel Efraín Rodríguez Rivera, Kevin Ulises López Martír, Judith Esmeralda Urías Silvas, Juan Alberto Resendiz Vazquez, Raúl Delgado Delgado, María Soledad Córdova Aguilar, Antonio Hidalgo Millan   +6 more
wiley   +1 more source

Treatment of Anaphylaxis in Adults: A Questionnaire Survey [PDF]

, 2009
Objective: To identify the medications that medical students, interns and casualty medical officers are likely to prescribe when treating an adult patient with anaphylaxis, and to ascertain the dose and route of administration of adrenaline they would ...
Adiga, Shalini, Nayak, Veena, Veena Nayak, Shalini Adiga, Bairy, KL, K.L Bairy   +5 more
core  

Indocyanine green for intraoperative ureteral identification in gynecologic surgery: A preliminary systematic review of feasibility, safety, and surgical outcomes

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Intraoperative ureteral injury, although uncommon, can result in significant morbidity and medicolegal consequences, particularly during complex gynecologic procedures such as endometriosis excision and prolapse repair. Conventional ureteral identification techniques, including stents and methylene blue, have recognized limitations.
Victoria Zhang, Dhruv Mantri, Qiannan Yang, Xiaoming Guan   +3 more
wiley   +1 more source

Anaphylaxis - Lessons learnt when East meets West

, 2019
The rapidly increasing prevalence of allergic disorders over the past 2 decades highlights the need to understand the epidemiology of anaphylaxis. In Europe, the United States, and Australia, the incidence of anaphylaxis is estimated to be between 60 and
Ebisawa, M, Tham, EH, Lee, BW, APAPARI Anaphylaxis Study Group, Wong, GWK, Pacharn, P, Leung, ASY, Lee, S   +7 more
core   +1 more source

Evaluation of Ceftriaxone as a Monotherapy and Amoxicillin With Clavulanic Acid as Combination Therapy in Surgical Prophylaxis

iNew Medicine, EarlyView.
ABSTRACT Surgical antibiotic prophylaxis (SAP) is crucial in preventing postoperative surgical site infections (SSIs), especially in clean and clean‐contaminated surgeries. It was a prospective comparative observational study that compared the effectiveness and safety of single‐dose ceftriaxone monotherapy with amoxicillin–clavulanic acid as a ...
Anayat Ullah, Arsh Ali, Md Nematullah, Suriya Kumar Singh, Anant Singh Paliwal, Najish Parveen   +5 more
wiley   +1 more source

Recognizing and responding to anaphylaxis [PDF]

Healthcare personnel should consider anaphylaxis when patients present with generalized signs or symptoms such as hives, serious or life-threatening symptoms (e.g., hypotension, respiratory distress, or significant swelling of the tongue or lips), or ...

core  

Clinical progress note: Mumps

Journal of Hospital Medicine, EarlyView.
Abstract Mumps was a common childhood viral illness before the implementation of the measles, mumps, and rubella (MMR) vaccination in 1967. There was a significant decrease in mumps cases in the postvaccine era; however, there has been an increase in outbreaks in the United States over the past two decades.
Sarah Ludvigsen, Mati Segev
wiley   +1 more source

Anaphylaxis

, 2023
Anaphylaxis is a serious condition that usually occurs suddenly and requires immediate treatment, which can lead to hypoxemia and/or shock and death. Nurses should be able to recognize early signs of anaphylaxis and know how to intervene appropriately ...
Dogan, D.A., Ayik, D.B.
core   +2 more sources