Results 71 to 80 of about 64,244 (297)

Evaluating the (comparative) safety profile of the novel oral polio vaccine type 2 using individual case safety reports in VigiBase

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar   +6 more
wiley   +1 more source

Identification of antibiotic allergies in children using prescribing patterns in the electronic medical record

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Background By age three, 5%–75% of children have a documented antibiotic allergy (AL). Despite this prevalence, recognition remains low because of limited clinician knowledge and time. Our study evaluates a novel approach to identifying AL using electronic medical record (EMR) prescription patterns.
Georgia Koutsaplis   +5 more
wiley   +1 more source

N‐acetylcysteine for non‐paracetamol‐induced acute liver failure in children: A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Non‐surgical treatment of acute liver failure (ALF) is primarily supportive and depends on the underlying cause. While N‐acetylcysteine (NAC) is proven effective in paracetamol‐induced ALF, its potential benefits in non‐paracetamol ALF for paediatric patients remain unclear.
Alise D. E. de Groot   +7 more
wiley   +1 more source

Anaphylaxis

open access: yesImmunology and Allergy Clinics of North America, 2015
Anaphylaxis is recently becoming an increasingly popular issue among allergists, particularly upon fatigue with asthma matters. The paper “Anaphylaxis as a cause of hospitalization—a single academic centre experience” published in this issue of “Polish Pneumonology and Allergology” follows this trend [...]
openaire   +5 more sources

Implementation of Rapid Drug Desensitization in Antineoplastic Drug Therapy in Denmark Using One‐Bag Protocols

open access: yesClinical and Translational Allergy
Background Rapid drug desensitization (RDD) is the cornerstone of managing patients with immediate drug hypersensitivity reactions (IDHR) to antineoplastic drugs in Southern Europe and the United States.
Trine Holm Rasmussen   +8 more
doaj   +1 more source

Infant anaphylaxis: the importance of early recognition [PDF]

open access: yes, 2013
A DosanjhDepartment of Pediatrics, Rady Children's Hospital, San Diego, CA, USAAbstract: Anaphylaxis is an acute severe reaction involving multiple systems that results from a rapid release of inflammatory mediators.
Dosanjh A
core  

Effects of Trimethoprim on Three Previously Proposed Putative Biomarkers for OCT2/MATE‐Mediated Renal Drug‐Drug Interactions in Healthy Volunteers

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Regulatory agencies request the assessment of the potential of new drugs to cause transporter‐mediated drug‐drug interactions (DDI). This assessment can be improved by integrating endogenous biomarkers during drug development. Regarding the renal excretion of drugs such as metformin, the organic cation transporter (OCT) 2 and multidrug and toxin ...
Jana Picurová   +5 more
wiley   +1 more source

“Effects of High‐Intensity Ultrasound on the Structural, Technofunctional, and Allergenic Properties of Groundnut (Arachis hypogaea L.) Protein Isolates: A Review”

open access: yesFood Chemistry International, EarlyView.
ABSTRACT The growing global demand for sustainable, nutritionally balanced protein sources has intensified interest in plant‐derived proteins, particularly those derived from oilseeds such as groundnut (Arachis hypogaea L.). However, although groundnut protein isolates (GPIs) have high nutritional quality, they exhibit limitations in technofunctional ...
Ángel Efraín Rodríguez Rivera   +6 more
wiley   +1 more source

Treatment of Anaphylaxis in Adults: A Questionnaire Survey [PDF]

open access: yes, 2009
Objective: To identify the medications that medical students, interns and casualty medical officers are likely to prescribe when treating an adult patient with anaphylaxis, and to ascertain the dose and route of administration of adrenaline they would ...
Adiga, Shalini   +5 more
core  

Indocyanine green for intraoperative ureteral identification in gynecologic surgery: A preliminary systematic review of feasibility, safety, and surgical outcomes

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Intraoperative ureteral injury, although uncommon, can result in significant morbidity and medicolegal consequences, particularly during complex gynecologic procedures such as endometriosis excision and prolapse repair. Conventional ureteral identification techniques, including stents and methylene blue, have recognized limitations.
Victoria Zhang   +3 more
wiley   +1 more source

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