Results 301 to 310 of about 102,570 (330)

Rapid food desensitization associated with omalizumab before oral immunotherapy. [PDF]

World Allergy Organ J
Giavina-Bianchi B, Giavina-Bianchi P.
europepmc   +1 more source

Perioperative Intravenous Lidocaine Infusion Therapy as an Adjunct to Multimodal Analgesia for Adolescent Idiopathic Scoliosis Surgical Correction: A Double‐Blind Randomized Controlled Trial

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Posterior spinal instrumentation and fusion is a common surgical correction for adolescent idiopathic scoliosis. Preventative multimodal analgesia, including opioids, is required to minimize postoperative pain, but opioids are associated with dose‐dependent side effects that may disrupt recovery.
Jessica Luo, Nicholas West, Samantha Pang, Aanisah Golam, Erin Adams, Matthias Görges, Roxane R. Carr, Firoz Miyanji, Gillian R. Lauder   +8 more
wiley   +1 more source

Rescuing Protamine Anaphylaxis Refractory to Adrenaline Using Extracorporeal Membrane Oxygenation. [PDF]

JACC Case Rep
Oda Y, Yamasaki H, Osawa T, Igarashi M, Ishizu T.   +4 more
europepmc   +1 more source

Clinical manifestations of Florida spot keratopathy in dogs and cats: One hundred cases (2021–2024)

Veterinary Ophthalmology, EarlyView.
Abstract Purpose This study describes the ocular findings in dogs and cats diagnosed with Florida spot keratopathy (FSK) at a single institution. Methods Affected animals underwent a single comprehensive ophthalmic examination, with no follow‐ups conducted. Data on patient demographics and clinical findings were collected and analyzed. Results Based on
O. Pe'er, K. W. Handel, D. Arad, L. Sebbag, R. Ofri   +4 more
wiley   +1 more source

Time to challenge penicillin allergy labels. [PDF]

Can Fam Physician
Braschi É, Moe SS.
europepmc   +1 more source

Amino Acid Stress Response Genes Contribute to a 25‐Fold Increased Risk of L‐Asparaginase–Induced Hypersensitivity

Pediatric Blood &Cancer, Volume 72, Issue 6, June 2025.
ABSTRACT Background L‐asparaginase is essential in treating pediatric acute lymphoblastic leukemia (ALL) but is limited by hypersensitivity reactions in up to 70% of patients, leading to severe, dose‐limiting complications and compromised event‐free survival. Procedure This study conducted a genome‐wide association study (GWAS) in a discovery cohort of
Spencer J. Anderson, Erika N. Scott, Edward J. Raack, Wan‐Chun Chang, Miguel Córdova‐Delgado, Jessica N. Trueman, Catrina M. Loucks, S. Rod. Rassekh, Colin J. D. Ross, Bruce C. Carleton, the Canadian Pharmacogenomics Network for Drug Safety (CPNDS) consortium   +10 more
wiley   +1 more source

Wrinkles Worries: Decoding Allergy Reactions to Botulinum Neurotoxin. [PDF]

J Cosmet Dermatol
Charlotte H.
europepmc   +1 more source

Beyond Efficacy: Ensuring Safety in Peptide Therapeutics through Immunogenicity Assessment

Journal of Peptide Science, Volume 31, Issue 6, June 2025.
Peptides are increasingly used in diagnosis and treatment due to their selectivity and low side effects. Over 11% of FDA‐approved drugs from 2016 to 2024 were synthetic peptides. However, immunogenicity—an adverse immune response—can limit their safety and efficacy.
Koulla Achilleos, Christos Petrou, Vicky Nicolaidou, Yiannis Sarigiannis   +3 more
wiley   +1 more source

Prehospital antibiotic administration for suspected open fractures: importance and implementation. [PDF]

Trauma Surg Acute Care Open
Levy MJ, Manukyan MC, Ficke JR.
europepmc   +1 more source