Results 161 to 170 of about 4,937 (255)
Prediction of the individual risk for the development of brain metastases in patients with non‐oncogene‐addicted non‐small cell lung cancer: Real‐world data from the German prospective CRISP registry (AIO‐TRK‐0315)
International Journal of Cancer, Volume 159, Issue 3, Page 739-749, 1 August 2026.What's New?
Estimating the risk of developing brain metastases may enable earlier diagnosis and treatment, potentially reducing morbidity and mortality. Using the prospective CRISP lung cancer registry, the authors developed and validated a point‐based classifier for the risk of developing first brain metastases in patients with advanced or metastatic ...Fabian Acker, Katharina Wenger, Martin Reck, Cornelius F. Waller, Petra Hoffknecht, Andre Bethge, Arnd Nusch, Marcel Reiser, Christiane Bernhardt, Michael Bendel, Carolin Lennartz, Annette Fleitz, Martina Jänicke, Paula Ludwig, Annika Groth, Frank Griesinger, Michael Thomas, Wilfried E. E. Eberhardt, Martin Sebastian, for the CRISP Registry Group, Juliana Ababei, Jürgen Alt, Andreas Ammon, Sven Philip Aries, Akin Atmaca, Ivo Azeh, Eva‐Maria Barkowsky, Stefan Bauer, Silvan Becker, Dirk Behringer, Michael Bendel, Robin Benkelmann, Veronika Berberich, André Bethge, Annalen Bleckmann, Michael Boesche, Sabine Bohnet, Harald‐Robert Bruch, Wolfgang Brückl, Ulrike Burkhard‐Meier, Dieter Bürkle, Daniel C. Christoph, Petros Christopoulos, Peter Czyborra, Klaus‐Ulrich Däßler, Maike de Wit, Tobias Dechow, Reinhard Depenbusch, Karl‐Matthias Deppermann, Nicolas Dickgreber, Lutz Dietze, Markus Dommach, Steffen Dörfel, Wilfried Eberhardt, Ekkehard Eigendorff, Corinna Elender, Wolfgang Elsel, Till‐Oliver Emde, Bastian Eul, Martin Faehling, Florian Fauth, Thomas Fietz, Dimitri Flieger, Helmut Forstbauer, Werner Freier, Christian Frenzel, Florian Fuchs, Roswitha Fuchs, Thomas Fühner, Tobias Gaska, Wolfgang Gleiber, Tobias Graefe, Ullrich Graeven, Christian Grah, Sibylle Greiner, Frank Griesinger, Christian Grohé, Matthias Groschek, Carolin Groß‐Ophoff‐Müller, Andreas Günther, Sylvia Gütz, Siegfried Haas, Matthias Hackenthal, Volker Hagen, Carla Verena Hannig, Richard Hansen, Andrea Heider, David Heigener, Kathrin Heinrich, Natalia Heinz, Christiane Hering‐Schubert, Jörg Heßling, Conrad Heuchel, Petra Hoffknecht, Patricia Hortig, Gerdt Hübner, Horst‐Dieter Hummel, Ulrich Hutzschenreuter, Gerald Illerhaus, Thomas Illmer, Georg Innig, Melanie Janning, Jan Janssen, Christian Junghanß, Christian Kaes, Ulrich Kaiser, Stefan Kaldune, Haytham Kamal, Kato Kambartel, Lale Kayikci, Jens Kern, Dorothea Kingreen, Ortwin Klein, Konrad Kokowski, Wolfgang Körber, Dirk Koschel, Benoit Krämer, Beate Krammer‐Steiner, Jonas Kuon, Eckart Laack, Christof Lamberti, Markus Lehmann, Rumo David Leistner, Rüdiger Liersch, Hartmut Linde, Migle Link, Jörg Lipke, Verena Luber, Andreas Lück, Gita Maher, Kerstin Martin, Martin Metzenmacher, Christian Meyerzum Büschenfelde, Philipp Meyn, Enno Moorahrend, Christian Mozek, Annette Müller, Lothar Müller, Michael Neise, Holger Nückel, Arnd Nusch, Tobias Overbeck, Matthias Paland, Henning Pelz, Volker Petersen, Bettina Peuser, Christian Plate, Margarete Plath, Stefan Pluntke, Munir Rababah, Martin Reck, Niels Reinmuth, Marcel Reiser, Roland Repp, Daniel Reschke, Achim Rittmeyer, Yolanda Rodemer, Georg Rußwurm, Parvis Sadjadian, Reiner Sandner, Annette Sauer, Harald Schäfer, Clemens Schiefer, Burkhard Schmidt, Stephan Schmitz, Folker Schneller, Jan Schröder, Gunter Schuch, Christoph Schulz, Christian Schulz, Mathias Schulze, Christian Schumann, Wolfgang Schütte, Martin Schwaiblmair, Marcus Schweigert, Peter Florian Schwindt, Martin Sebastian, Bernd Seese, Gernot Seipelt, Christoph Sick, Theodoros Skentos, Thomas Sorgenfrei, Axel Stang, Johannes Steiff, Heike Steiniger, Susanne Stetter, Runa Stiegler, Heidrun Stumme, Amanda Tufman, Jens Uhlig, Ursula Vehling‐Kaiser, Gunther Vogel, Eyck von der Heyde, Oliver Waidmann, Cornelius F. Waller, Georg Weißenborn, Florian Weißinger, Martin Wermke, Claas Wesseler, Jörg Wiegand, Ute Wieschermann, Stefan Wilhelm, Jochen Wilke, Mark‐Oliver Zahn, Matthias Zaiss, Matthias Zeth, Joachim Zimber, Björn Schöttker +207 morewiley +1 more sourcePrimary CNS Anaplastic Large Cell Lymphoma DUPS22 Rearranged with Gain of ALK: A Case Report and Review of the Literature
eJHaem, Volume 7, Issue 4, August 2026.ABSTRACT ALK‐negative anaplastic large cell lymphoma (ALCL) is a rare primary central nervous system lymphoma (PCNSL). Although DUSP22 rearrangement is considered favorable in systemic ALK‐negative ALCL, survival remains poor in PCNSL. We report a case of PCNSL ALK‐negative ALCL with DUSP22‐IRF4 rearrangement and an unusual gain of the ALK gene (2p23), Sindu Iska, María Herrán, Zackary Anderson, Pablo Bejarano, Silvia Bunting, Chieh‐Lin Fu +5 morewiley +1 more sourceThe malignant transformation of an atypical angiocentric glioma, MYB-altered. [PDF]
Acta Neuropathol CommunAboubakr O, Wefers AK, Dangouloff-Ros V, Métais A, Sievers P, Hasty L, Saffroy R, Pierron G, Guillemot D, Samoyeau T, Boddaert N, Grill J, Beccaria K, Blauwblomme T, Varlet P, Tauziède-Espariat A. +15 moreeuropepmc +1 more sourceAntibody–Drug Conjugates and Peptide–Drug Conjugates: Current Understandings and Future Perspectives
MedComm, Volume 7, Issue 8, August 2026.The graphic summarizes the design principles, intracellular trafficking, clinical progress, challenges, and future directions of antibody–drug conjugates (ADCs) and peptide–drug conjugates (PDCs). ADCs consist of a tumor‐targeting antibody, a chemical linker, and a potent payload, whereas PDCs use peptide ligands to deliver cytotoxic, radionuclide, or ...Ruxi Zheng, Shuiquan Li, Zhigang Zhang, Mengke Niu, Jing Fei, Jiaojiao Zhang, Jianwei Zhou, Kongming Wu, Ming Yi, Tianye Li +9 morewiley +1 more sourceQuantitative Imaging of Pyruvate Metabolism in a Patient With Anaplastic Thyroid Cancer
Magnetic Resonance in Medicine, Volume 96, Issue 2, Page 826-838, August 2026.ABSTRACT Purpose
Magnetic resonance imaging using hyperpolarized (HP) [1‐13C]‐pyruvate enables assessment of pyruvate metabolism in vivo and offers new insight into metabolic changes in response to cancer therapy. Widely used semi‐quantitative metrics of pyruvate metabolism can be affected by physiological factors that are extrinsic to intracellular ...James A. Bankson, Joshua S. Niedzielski, Collin J. Harlan, Yunyun Chen, Christopher M. Walker, Philip L. Lorenzi, Lin Tan, Vikas Kundra, Matthew E. Merritt, Mukundan Ragavan, Dawid Schellingerhout, Renjie He, Yao Ding, Sahana Datar, Qing Wang, Christine B. Peterson, Clifton D. Fuller, Vlad C. Sandulache, Stephen Y. Lai +18 morewiley +1 more sourceThe Role of Thyroidectomy in the Management of Thyroglossal Duct Carcinoma: A Systematic Review
Otolaryngology–Head and Neck Surgery, Volume 175, Issue 2, Page 271-280, August 2026.Abstract Objective
The extent of surgical management of thyroglossal duct‐associated differentiated thyroid carcinoma remains controversial. This study aims to evaluate the role of total thyroidectomy in patients with thyroglossal duct‐associated differentiated thyroid carcinoma and provide insights to support individualized, evidence‐based care.Hidde H. IJtsma, Sam P. J. van Dijk, Carrie E. Cunningham, Folkert J. van Kemenade, Robin P. Peeters, Stijn Keereweer, Tessa M. van Ginhoven +6 morewiley +1 more source