Results 1 to 10 of about 47,472 (162)
CNS Oncology, 2016 Anaplastic astrocytoma (AA) is a diffusely infiltrating, malignant, astrocytic, primary brain tumor. AA is currently defined by histology although future classification schemes will include molecular alterations. AA can be separated into subgroups, which share similar molecular profiles, age at diagnosis and median survival, based on 1p/19q co-deletion
Marc Chamberlain, Sean Grimm
exaly +3 more sources
Pilomyxoid astrocytoma of the brainstem
Rare Tumors, 2013 A pilomyxoid astrocytoma is a recently described tumor that occurs predominantly in the hypothalamic-chiasmatic region and is rarely found elsewhere. It has similar features as pilocytic astrocytomas, but has distinct histological characteristics and a ...
Marco Antonio Zanini +6 more
doaj +5 more sources
Childhood cerebellar astrocytoma, surgical management [PDF]
Minia Journal of Medical Research, 2022 Background: Cerebellar astrocytomas account for approximately 12 to 17% of all CNS tumors in the pediatric age group and 25 to 35% of childhood posterior fossa tumors.
Medhat El-Sawy +2 more
doaj +1 more source
Expression of P53 and Ki-67 in Different Grades of Astrocytomas [PDF]
International Journal of Medical Arts, 2022 Background: Astrocytomas are considered the most prevalent central nervous system [CNS] tumors. Diffuse astrocytomas are evaluated by a three-tiered system [II, III, and IV] according to the 2007 WHO classification. The WHO grading scheme is based on the
Rania Rifat Abdel-Maqsoud Mohamed +1 more
doaj +1 more source
BMC Cancer, 2021 Background Astrocytoma is a common type of central nervous system tumor. In this study, we investigated the correlation between ST6GAL1 and CYP19A1 polymorphisms and the risk and prognosis of astrocytoma.
Tuo Wang +6 more
doaj +1 more source
Inhibition of STAT3 reduces astrocytoma cell invasion and constitutive activation of STAT3 predicts poor prognosis in human astrocytoma. [PDF]
PLoS ONE, 2013 Astrocytoma cells characteristically possess high invasion potentials. Recent studies have revealed that knockdown of signal transducers and activators of transcription 3 (STAT3) expression by RNAi induces apoptosis in astrocytoma cell. Nevertheless, the
Qinchuan Liang +4 more
doaj +1 more source
Frontiers in Oncology, 2021 The pro-oncogene ETS-1 (E26 transformation-specific sequence 1) is a key regulator of the proliferation and invasion of cancer cells. The present work examined the correlation of the aberrant expression of ETS-1 with histological or clinical ...
Junping Wang +6 more
doaj +1 more source
A 16-gene signature distinguishes anaplastic astrocytoma from glioblastoma. [PDF]
PLoS ONE, 2014 Anaplastic astrocytoma (AA; Grade III) and glioblastoma (GBM; Grade IV) are diffusely infiltrating tumors and are called malignant astrocytomas. The treatment regimen and prognosis are distinctly different between anaplastic astrocytoma and glioblastoma ...
Soumya Alige Mahabala Rao +9 more
doaj +1 more source
IMMUNOHISTOCHEMICAL EXPRESSION OF CLUSTER OF DIFFERENTIATION-68(CD-68) AND KI-67 IN ASTROCYTOMAS [PDF]
Zagazig University Medical Journal, 2014 Background: Astrocytoma is common primary malignant brain tumors which arise from immortalized astrocytes. In astrocytoma microglia density is higher than in normal brain, and microglia increase in number according to the grade of malignancyIntense CD68 ...
Elkateb M. +3 more
doaj +1 more source
Glutamate Signaling and Filopodiagenesis of Astrocytoma Cells in Brain Cancers: Survey and Questions
Cells, 2022 Astrocytes are non-excitable cells in the CNS that can cause life-threatening astrocytoma tumors when they transform to cancerous cells. Perturbed homeostasis of the neurotransmitter glutamate is associated with astrocytoma tumor onset and progression ...
Mitra Tabatabaee, Frederic Menard
doaj +1 more source