Results 11 to 20 of about 46,157 (226)

Pilomyxoid Astrocytoma of the Brainstem

Rare Tumors, 2013
A pilomyxoid astrocytoma is a recently described tumor that occurs predominantly in the hypothalamic-chiasmatic region and is rarely found elsewhere. It has similar features as pilocytic astrocytomas, but has distinct histological characteristics and a poorer prognosis.
Pereira, Francisco Otavio, Lombardi, Ismael Augusto, Mello, Adriana Yuki, Romero, Flavio Ramalho, Ducati, Luis Gustavo, Gabarra, Roberto Colichio, Zanini, Marco Antonio   +6 more
openaire   +6 more sources

Childhood cerebellar astrocytoma, surgical management [PDF]

Minia Journal of Medical Research, 2022
Background: Cerebellar astrocytomas account for approximately 12 to 17% of all CNS tumors in the pediatric age group and 25 to 35% of childhood posterior fossa tumors.
Medhat El-Sawy, Mohamed Abdallah, Ahmed Moawad   +2 more
doaj   +1 more source

Expression of P53 and Ki-67 in Different Grades of Astrocytomas [PDF]

International Journal of Medical Arts, 2022
Background: Astrocytomas are considered the most prevalent central nervous system [CNS] tumors. Diffuse astrocytomas are evaluated by a three-tiered system [II, III, and IV] according to the 2007 WHO classification. The WHO grading scheme is based on the
Rania Rifat Abdel-Maqsoud Mohamed, Mohamed Yousef Ali   +1 more
doaj   +1 more source

Association of ST6GAL1 and CYP19A1 polymorphisms in the 3′-UTR with astrocytoma risk and prognosis in a Chinese Han population

BMC Cancer, 2021
Background Astrocytoma is a common type of central nervous system tumor. In this study, we investigated the correlation between ST6GAL1 and CYP19A1 polymorphisms and the risk and prognosis of astrocytoma.
Tuo Wang, Yao Sun, Zichao Xiong, Jiamin Wu, Xiaoying Ding, Xiaoye Guo, Yuan Shao   +6 more
doaj   +1 more source

Inhibition of STAT3 reduces astrocytoma cell invasion and constitutive activation of STAT3 predicts poor prognosis in human astrocytoma. [PDF]

PLoS ONE, 2013
Astrocytoma cells characteristically possess high invasion potentials. Recent studies have revealed that knockdown of signal transducers and activators of transcription 3 (STAT3) expression by RNAi induces apoptosis in astrocytoma cell. Nevertheless, the
Qinchuan Liang, Chenkai Ma, Yang Zhao, Guodong Gao, Jie Ma   +4 more
doaj   +1 more source

Hypermethylation of the Promoter of miR-338-5p Mediates Aberrant Expression of ETS-1 and Is Correlated With Disease Severity Of Astrocytoma Patients

Frontiers in Oncology, 2021
The pro-oncogene ETS-1 (E26 transformation-specific sequence 1) is a key regulator of the proliferation and invasion of cancer cells. The present work examined the correlation of the aberrant expression of ETS-1 with histological or clinical ...
Junping Wang, Junping Wang, Cheng Huo, Jinzhu Yin, Lixia Tian, Lili Ma, Dongsheng Wang   +6 more
doaj   +1 more source

A 16-gene signature distinguishes anaplastic astrocytoma from glioblastoma. [PDF]

PLoS ONE, 2014
Anaplastic astrocytoma (AA; Grade III) and glioblastoma (GBM; Grade IV) are diffusely infiltrating tumors and are called malignant astrocytomas. The treatment regimen and prognosis are distinctly different between anaplastic astrocytoma and glioblastoma ...
Soumya Alige Mahabala Rao, Sujaya Srinivasan, Irene Rosita Pia Patric, Alangar Sathyaranjandas Hegde, Bangalore Ashwathnarayanara Chandramouli, Arivazhagan Arimappamagan, Vani Santosh, Paturu Kondaiah, Manchanahalli R Sathyanarayana Rao, Kumaravel Somasundaram   +9 more
doaj   +1 more source

Glutamate Signaling and Filopodiagenesis of Astrocytoma Cells in Brain Cancers: Survey and Questions

Cells, 2022
Astrocytes are non-excitable cells in the CNS that can cause life-threatening astrocytoma tumors when they transform to cancerous cells. Perturbed homeostasis of the neurotransmitter glutamate is associated with astrocytoma tumor onset and progression ...
Mitra Tabatabaee, Frederic Menard
doaj   +1 more source

Novel insight into histological and molecular astrocytoma, IDH‐mutant, Grade 4 by the updated WHO classification of central nervous system tumors

Cancer Medicine, 2023
Background The latest fifth edition of the World Health Organization (WHO) classification of the central nervous system (CNS) tumors (WHO CNS 5 classification) released in 2021 defined astrocytoma, IDH‐mutant, Grade 4.
Wenlin Chen, Siying Guo, Yaning Wang, Yixin Shi, Xiaopeng Guo, Delin Liu, Yilin Li, Yuekun Wang, Hao Xing, Yu Xia, Junlin Li, Jiaming Wu, Tingyu Liang, Hai Wang, Qianshu Liu, Shanmu Jin, Tian Qu, Huanzhang Li, Tianrui Yang, Kun Zhang, Yu Wang, Wenbin Ma   +21 more
doaj   +1 more source

Nucleolar and spindle associated protein 1 promotes the aggressiveness of astrocytoma by activating the Hedgehog signaling pathway

Journal of Experimental & Clinical Cancer Research, 2017
Background The prognosis of human astrocytoma is poor, and the molecular alterations underlying its pathogenesis still needed to be elucidated. Nucleolar and spindle associated protein 1 (NUSAP1) was observed in several types of cancers, but its role in ...
Xianqiu Wu, Benke Xu, Chao Yang, Wentao Wang, Dequan Zhong, Zhan Zhao, Longshuang He, Yuanjun Hu, Lili Jiang, Jun Li, Libing Song, Wei Zhang   +11 more
doaj   +1 more source