Results 41 to 50 of about 46,157 (226)
Archives of Otolaryngology - Head and Neck Surgery, 1956 To the generic group of the gliomas belong the tumors designated astrocytomas, and, according to Ewing, * these neoplasias are, in general, cerebral or cerebellar tumors of slow growth, composed principally of adult glial cells. The astrocytomas have a special structure and are relatively acellular and scarcely vascularized.
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PLoS ONE, 2020 Childhood cancers are increasingly recognized as disorders of cellular development. This study sought to identify the cellular and developmental origins of cerebellar pilocytic astrocytoma, the most common brain tumor of childhood.
Subhi Talal Younes, Betty Herrington
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Expression of Ki 67 and P53 immunohistochemical markers in central nervous system astrocytoma
مجلة كلية الطب, 2015 Background: Astrocytic tumors are the most common primary tumors of the central nervous system. Several grading systems are used to grade astrocytomas.
Mahmood Sh. Mahmood +1 more
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SAGE Open Medical Case Reports, 2018 Optic nerve pilocytic astrocytoma is an uncommon but well-known entity; however, intraorbital ancient pilocytic astrocytoma of the optic nerve is extremely rarely reported.
Haesu Lee Motoyama +4 more
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Indian Journal of Pathology and Microbiology, 2010 Pilomyxoid astrocytoma (PMA) is a recently described brain tumor. PMA shares similar features with pilocytic astrocytoma (PA), the most common central nervous system (CNS) tumor in the pediatric population, yet displays subtle histologic differences.
Azad Sheenam +6 more
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
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Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang +4 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
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Evaluation of Brain Tumours using Magnetic Resonance Perfusion Imaging: A Prospective Study [PDF]
Journal of Clinical and Diagnostic Research, 2020 Introduction: Brain tumours are an important cause of neurological problems. Grade of these tumours is one of the parameters which decide the treatment offered to patients. Magnetic Resonance Imaging (MRI) though superior to other conventional modalities
Darshan Singh Grewal +4 more
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