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Anaplasia in Pilocytic Astrocytoma Predicts Aggressive Behavior
American Journal of Surgical Pathology, 2010The clinical significance of anaplastic features, a rare event in pilocytic astrocytoma (PA), is not fully established. We reviewed 34 PA with anaplastic features (Male = 21, Female = 13; median age 35 y, 5 to 75) among approximately 2200 PA cases (1.7%).
Fausto J, Rodriguez +4 more
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c-Myc Overexpression Causes Anaplasia in Medulloblastoma
Cancer Research, 2006AbstractBoth anaplasia and increased c-myc gene expression have been shown to be negative prognostic indicators for survival in medulloblastoma patients. myc gene amplification has been identified in many large cell/anaplastic medulloblastoma, but no causative link between c-myc and anaplastic changes has been established.
Duncan, Stearns +5 more
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H3 K27M Mutations in Thalamic Pilocytic Astrocytomas with Anaplasia
World Neurosurgery, 2019The revised World Health Organization classification of central nervous system tumors, published in 2016, has recognized the H3 K27M mutation as a critical genetic signature defining a new group of infiltrative astrocytomas designated as diffuse midline glioma, H3 K27M mutant.
Tarek Y. El Ahmadieh +9 more
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Vincristine, Irinotecan, and Bevacizumab in Relapsed Wilms Tumor With Diffuse Anaplasia
Journal of Pediatric Hematology/Oncology, 2018The prognosis of relapsed Wilms tumor (WT) with diffuse anaplasia is dismal, therefore, novel therapeutic strategies need to be explored. We reported on 2 consecutive cases with relapsed anaplastic WT who presented a partial response after 2 courses of vincristine, irinotecan, and bevacizumab association.
Schiavetti, Amalia +3 more
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Leukemic Anaplasias Reflecting Physiologic Cytogenesis of Myeloid System
1976Naphthol AS-D chloroacetatesterase activity in peripheral blood granulocytes is confined to neutrophils which are all positive and to a minor part of monocytes. Its occurance in eosinophils and basophils indicate a myeloproliferative disease. This chemical property can reliably be applied to separate neoplastic from reactive forms of quantitative and ...
M R, Parwaresch +2 more
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Differentiation and Anaplasia in Central Neuroepithelial Tumors
2015L J, Rubinstein +2 more
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