Results 111 to 120 of about 125,680 (260)

Phase 1/2 Study of Crizotinib in Children With Relapsed/Refractory ALK‐Positive Anaplastic Large Cell Lymphoma or Neuroblastoma in Japan

Cancer Science, EarlyView.
The safety and antitumor activity of crizotinib at a dose of 165 mg/m2 BID were evaluated in 16 patients with ALK‐positive ALCL in Japan. The most common grade 3 or 4 adverse event was neutropenia. The steady‐state Cmax and AUCtau of crizotinib at 165 mg/m2 BID were higher than expected. The objective response rate was 72.7% (90% CI, 43.6%–92.1%) among
Tetsuya Mori, Akiko Kada, Tomoo Osumi, Daisuke Tomizawa, Yuhki Koga, Reiji Fukano, Kengo Takeuchi, Ukihide Tateishi, Osamu Miyazaki, Ryuta Asada, Akiko M. Saito, Kei Fukuhara, Masahiro Sekimizu   +12 more
wiley   +1 more source

ALK1-Negative Anaplastic Large Cell Lymphoma of the Breast from a Nonprosthesis Cyst

Plastic and Reconstructive Surgery, Global Open, 2014
Summary: Anaplastic large cell lymphoma of the breast is a rare malignancy associated with prosthetic breast implants. We present a case of a woman with no prior history of breast implants who developed anaplastic lymphoma kinase-1 negative anaplastic ...
Christopher Mulligan, MBBS, Elizabeth Salisbury, MBBS, Mark Tschuchnigg, MBBS, Pouria Moradi, MBBS, Alexander Matthews, MBBS, Sanjay Warrier, MBBS   +5 more
doaj   +1 more source

Precision Oncology for Pediatric Solid Tumors Using In‐Hospital Pediatric/AYA Malignancy‐Specific Panel Sequencing

Cancer Science, EarlyView.
Our findings indicate that a pediatric/AYA‐specific targeted panel deployed in a hospital can deliver rapid, clinically actionable molecular insights with high diagnostic and prognostic yield. This complements larger sequencing platforms by offering speed, focused content, and easier interpretation.
Masato Kojima, Sho Kurihara, Isamu Saeki, Ryo Touge, Keigo Nakashima, Shuhei Karakawa, Fumiyuki Yamasaki, Satoshi Okada, Eiso Hiyama   +8 more
wiley   +1 more source

Synchronous occurrence of anaplastic, follicular and papillary carcinomas with follicular adenoma in thyroid gland

Indian Journal of Pathology and Microbiology, 2010
Various combinations of thyroid carcinomas have been reported including those between different cancers of follicular cell origin and those between follicular and C-cell histogenesis.
Ganguly R, Mitra S, Datta A
doaj  

Anaplastic Transformation of Papillary Thyroid Cancer in the Retroperitoneum

Case Reports in Pathology, 2015
Anaplastic thyroid carcinoma is an aggressive variant of thyroid cancer that in most cases arises from anaplastic transformation of terminally differentiated thyroid carcinomas.
James P. Solomon, Fang Wen, Lily J. Jih
doaj   +1 more source

ALK-positive anaplastic large cell lymphoma limited to the skin: clinical, histopathological and molecular analysis of 6 pediatric cases. A report from the ALCL99 study

Haematologica, 2013
Anaplastic large cell lymphomas are peripheral T-cell lymphomas that are characterized by a proliferation of large anaplastic blasts expressing CD30.
Ilske Oschlies, Jasmin Lisfeld, Laurence Lamant, Atsuko Nakazawa, Emanuele S. G. d'Amore, Ulrika Hansson, Konnie Hebeda, Ingrid Simonitsch-Klupp, Jadwiga Maldyk, Leonhard Müllauer, Marianne Tinguely, Markus Stücker, Marie-Cecile LeDeley, Reiner Siebert, Alfred Reiter, Laurence Brugières, Wolfram Klapper, Wilhelm Woessmann   +17 more
doaj   +1 more source

A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse. [PDF]

, 2000
A randomized, multicentre, open-label, phase II study compared temozolomide (TMZ), an oral second-generation alkylating agent, and procarbazine (PCB) in 225 patients with glioblastoma multiforme at first relapse.
Albright, RE, Brada, M, Bruner, J, Fink, K, Fredericks, R, Friedman, H, Glantz, M, Greenberg, H, Hohl, RJ, Levin, VA, Olson, J, Osoba, D, Phillips, P, Prados, MD, Rampling, R, Selker, RG, Shapiro, W, Spence, A, Vick, NA, Yue, N, Yung, WK, Zaknoen, S   +21 more
core  

Four‐Year Outcomes for Nivolumab With Chemotherapy and Bevacizumab in Patients With Nonsquamous NSCLC in the TASUKI‐52

Cancer Science, EarlyView.
This follow‐up study for TASUKI‐52 trial demonstrates the 4‐year beneficial efficacy of nivolumab (NIV) combined with chemotherapy (CP) and bevacizumab (BEV) in patients with nonsquamous non‐small cell lung cancer (NSCLC) and reveals potential patient backgrounds associated with long‐term survival.
Jong‐Seok Lee, Shunichi Sugawara, Jin‐Hyoung Kang, Hye Ryun Kim, Naoki Inui, Toyoaki Hida, Ki Hyeong Lee, Tatsuya Yoshida, Hiroshi Tanaka, Cheng‐Ta Yang, Takako Inoue, Makoto Nishio, Yasushi Goto, Tomohide Tamura, Nobuyuki Yamamoto, Chong‐Jen Yu, Hiroaki Akamatsu, Shigeru Takahashi, Kazuhiko Nakagawa   +18 more
wiley   +1 more source

Functional radical cervical dissection for differentiated thyroid cancer: the experience of a single center [PDF]

, 2018
There is ongoing debate regarding the role of neck dissection in differentiated thyroid cancer, about its usefulness in elective settings, and the increased costs regarding morbidity and operative time.
Adrian, Tulin, Alecu, Lucian, Cristian, Balalau, Hainarosie, Razvan, Jecan, Radu, Nitipir, Cornelia, Orlov, Cristina, Pantea Stoian, Anca, Pituru, Silviu, Poiana, Catalina, Slavu, Iulian, Tomescu, Luminita, Tulin, Raluca   +12 more
core   +1 more source

Cortical Anaplastic Ependymoma with Significant Desmoplasia: A Case Report and Literature Review

Case Reports in Oncological Medicine, 2013
Ectopic brain anaplastic ependymomas with no connection to the ventricles are rare. We present a rare case of a 25-year-old male who presented with generalized convulsions.
Alaa Eldin Elsharkawy, Raid Abuamona, Markus Bergmann, Shadi Salem, Evariste Gafumbegete, Ernst Röttger   +5 more
doaj   +1 more source