Results 1 to 10 of about 14,848,284 (309)

Molecular Characterization and Prognostication of Large Cell Neuroendocrine Carcinoma and Large Cell Carcinoma [PDF]

open access: yesFrontiers in Oncology, 2022
PurposeLarge cell neuroendocrine carcinoma (LCNEC) and classic large cell carcinoma (LCC) are two distinct entities with different histological and biological characteristics. However, the mutational profiles and the clinical behavior of the two subtypes
Ying Chen   +7 more
doaj   +3 more sources

Silicone breast prosthesis explant: breast reconstruction using the crossed flap technique [PDF]

open access: yesRevista Brasileira de Cirurgia Plástica, 2022
Introduction: In 1963 Cronin and Gerow introduced the use of the silicone implant and its use increased exponentially. However, complications related to implants emerged over time.
Ognev Meireles Cosac   +4 more
doaj   +1 more source

Primary large-cell neuroendocrine carcinoma of the prostate [PDF]

open access: yesArchives of the Balkan Medical Union, 2022
Introduction. Depending on neuroendocrine differentiation, the prostate cancer is divided into two major groups: primary neuroendocrine prostate tumour (carcinoid, small-cell, and large-cell neuroendocrine carcinoma) or as a focal tumour in conventional ...
Spasimir T. SHOPOV
doaj   +1 more source

Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) [PDF]

open access: yesLiječnički vjesnik, 2022
Anaplastic large cell lymphoma (ALCL) is a rare subtype of non-Hodgkin lymphoma (NHL) and it originates from mature T lymphocytes. Its subtypes are primary cutaneous ALCL (PC-ALCL), two subtypes of systemic ALCL (ALK-positive and ALK-negative), and ...
Marko Lagančić, Srećko Budi
doaj   +1 more source

Understanding Silicone Breast Implant-Associated Complications for Radiologists

open access: yes대한영상의학회지, 2021
With the increase in the number of cases of silicone implant insertion either for cosmetic surgery or breast reconstruction after mastectomy, it is not unusual to encounter patients with silicone implants in clinical settings.
Jeongmin Lee   +3 more
doaj   +1 more source

Production of Highly Uniform Midbrain Organoids from Human Pluripotent Stem Cells

open access: yesStem Cells International, 2023
Brain organoids have been considered as an advanced platform for in vitro disease modeling and drug screening, but numerous roadblocks exist, such as lack of large-scale production technology and lengthy protocols with multiple manipulation steps ...
Xuerui Yao   +18 more
doaj   +1 more source

Selective translation of epigenetic modifiers affects the temporal pattern and differentiation of neural stem cells

open access: yesNature Communications, 2022
The temporal development of tissues and organs may be defined by the genome-wide epigenetic and transcriptional state functioning as the clock. Here the authors found that Fbl, a ribosomal RNA methyltransferase, potentially behaves as a clock during ...
Quan Wu   +7 more
doaj   +1 more source

Open label safety and efficacy pilot to study mitigation of equine recurrent uveitis through topical suppressor of cytokine signaling-1 mimetic peptide

open access: yesScientific Reports, 2022
Equine recurrent uveitis (ERU) is a painful and debilitating autoimmune disease and represents the only spontaneous model of human recurrent uveitis (RU).
Caryn E. Plummer   +11 more
doaj   +1 more source

Mini-PE, a prime editor with compact Cas9 and truncated reverse transcriptase

open access: yesMolecular Therapy: Nucleic Acids, 2023
Prime editor (PE) is a versatile genome editing tool that does not need extra DNA donors or inducing double-strand breaks. However, in vivo implementation of PE remains a challenge because of its oversized composition.
Ting Lan   +14 more
doaj   +1 more source

The role of extracellular vesicles in animal reproduction and diseases

open access: yesJournal of Animal Science and Biotechnology, 2022
Extracellular vesicles (EVs) are nanosized membrane-enclosed compartments that serve as messengers in cell-to-cell communication, both in normal physiology and in pathological conditions.
Sangiliyandi Gurunathan   +4 more
doaj   +1 more source

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