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Molecular Characterization and Prognostication of Large Cell Neuroendocrine Carcinoma and Large Cell Carcinoma [PDF]
PurposeLarge cell neuroendocrine carcinoma (LCNEC) and classic large cell carcinoma (LCC) are two distinct entities with different histological and biological characteristics. However, the mutational profiles and the clinical behavior of the two subtypes
Ying Chen +7 more
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Silicone breast prosthesis explant: breast reconstruction using the crossed flap technique [PDF]
Introduction: In 1963 Cronin and Gerow introduced the use of the silicone implant and its use increased exponentially. However, complications related to implants emerged over time.
Ognev Meireles Cosac +4 more
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Primary large-cell neuroendocrine carcinoma of the prostate [PDF]
Introduction. Depending on neuroendocrine differentiation, the prostate cancer is divided into two major groups: primary neuroendocrine prostate tumour (carcinoid, small-cell, and large-cell neuroendocrine carcinoma) or as a focal tumour in conventional ...
Spasimir T. SHOPOV
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Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) [PDF]
Anaplastic large cell lymphoma (ALCL) is a rare subtype of non-Hodgkin lymphoma (NHL) and it originates from mature T lymphocytes. Its subtypes are primary cutaneous ALCL (PC-ALCL), two subtypes of systemic ALCL (ALK-positive and ALK-negative), and ...
Marko Lagančić, Srećko Budi
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Understanding Silicone Breast Implant-Associated Complications for Radiologists
With the increase in the number of cases of silicone implant insertion either for cosmetic surgery or breast reconstruction after mastectomy, it is not unusual to encounter patients with silicone implants in clinical settings.
Jeongmin Lee +3 more
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Production of Highly Uniform Midbrain Organoids from Human Pluripotent Stem Cells
Brain organoids have been considered as an advanced platform for in vitro disease modeling and drug screening, but numerous roadblocks exist, such as lack of large-scale production technology and lengthy protocols with multiple manipulation steps ...
Xuerui Yao +18 more
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The temporal development of tissues and organs may be defined by the genome-wide epigenetic and transcriptional state functioning as the clock. Here the authors found that Fbl, a ribosomal RNA methyltransferase, potentially behaves as a clock during ...
Quan Wu +7 more
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Equine recurrent uveitis (ERU) is a painful and debilitating autoimmune disease and represents the only spontaneous model of human recurrent uveitis (RU).
Caryn E. Plummer +11 more
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Mini-PE, a prime editor with compact Cas9 and truncated reverse transcriptase
Prime editor (PE) is a versatile genome editing tool that does not need extra DNA donors or inducing double-strand breaks. However, in vivo implementation of PE remains a challenge because of its oversized composition.
Ting Lan +14 more
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The role of extracellular vesicles in animal reproduction and diseases
Extracellular vesicles (EVs) are nanosized membrane-enclosed compartments that serve as messengers in cell-to-cell communication, both in normal physiology and in pathological conditions.
Sangiliyandi Gurunathan +4 more
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