Results 111 to 120 of about 96,938 (286)

Cortical Anaplastic Ependymoma with Significant Desmoplasia: A Case Report and Literature Review

Case Reports in Oncological Medicine, 2013
Ectopic brain anaplastic ependymomas with no connection to the ventricles are rare. We present a rare case of a 25-year-old male who presented with generalized convulsions.
Alaa Eldin Elsharkawy, Raid Abuamona, Markus Bergmann, Shadi Salem, Evariste Gafumbegete, Ernst Röttger   +5 more
doaj   +1 more source

Anaplastic carcinoma

, 1997
Anaplastic ...

core  

AOSNP‐ADAPTR resource level‐based recommendations on practical diagnostic strategies for medulloblastomas and other embryonal tumors

Brain Pathology, EarlyView.
Resource level‐based recommendations on practical diagnostic strategies for medulloblastomas and other CNS embryonal tumors are provided. Abstract WHO CNS5 mandates integrated histo‐molecular classification of medulloblastomas (MBs) and other CNS embryonal tumors. However, advanced molecular diagnostics remain inaccessible in many low‐ and lower‐middle‐
Chitra Sarkar, Maysa Al‐Hussaini, Vani Santosh, Vaishali Suri, Sung‐Hye Park, Yue‐Shan Piao, Tarik Tihan, Ho‐Keung Ng, Michael Buckland, Rakesh Jalali, Yonehiro Kanemura, Pieter Wesseling, Takashi Komori   +12 more
wiley   +1 more source

Molecular profiling of pediatric medulloblastoma in Kazakhstan: Genomic alterations, subgroup distribution, and survival

Brain Pathology, EarlyView.
A practical formalin‐fixed, paraffin‐embedded (FFPE)‐based molecular workflow integrating pathology, immunohistochemistry, and genomic profiling provides clinically meaningful subgroup classification of pediatric medulloblastoma and expands molecular evidence from an underrepresented Central Asian population. Abstract Medulloblastoma is the most common
Aidos Bolatov, Askhat Zhakupov, Aizhan Abdikadirova, Malika Sapargaliyeva, Bakytkali Ibraimov, Zhanat Zhalimbetova, Gabit Ólenbay, Berik Zhetpisbayev, Xingzhi Xu, Mirgul Bayanova   +9 more
wiley   +1 more source

Anaplastic thyroid carcinoma

, 2017
Anaplastic thyroid carcinoma (ATC) is a highly aggressive thyroid malignancy composed of undifferentiated follicular thyroid ...
Nikiforov Ye, Wick Mr, Westra W, Kebebew E, Matias-guiu X, Fagin Ja, Giuffrida D, El-naggar Ak, Sugitani I, Tallini G, Baloch Zw, Fellegara G, Kondo T, Wakely Pe, Evans Hl, Papotti M, Williams Md, Katoh R, Smallridge R, Franssila Ko, Eng C, Faquin W   +21 more
core   +1 more source

ALK (anaplastic lymphoma kinase)

, 1997
Review on ALK (anaplastic lymphoma kinase), with data on DNA, on the protein encoded, and where the gene is ...
Huret, JL, JL Huret
core   +1 more source

Anaplastic Sarcoma of the Kidney [PDF]

, 2020
We present a case of an extremely rare and relatively new tumor entity of the kidney, the anaplastic sarcoma. Although of unknown origin and pathogenesis, treating such a tumor as if it was anaplastic Wilms' tumor seems to be the only therapeutic ...
Reinhold Nützel, Vahudin Zugor, Apostolos P Labanaris, Reinhard Kühn, Robert Smiszek   +4 more
core  

Cardiotoxicity of BRAF/MEK inhibitors

British Journal of Pharmacology, EarlyView.
Abstract Rapidly accelerated fibrosarcoma type B/B‐Raf proto‐oncogene, serine/threonine kinase (BRAF) and mitogen‐activated protein kinase (MEK) inhibitors have transformed outcomes in cancer therapy, particularly in melanoma. However, cardiovascular toxicities are increasingly recognized in real‐world clinical practice.
Katharina Seuthe, Valerie Lohner, Kevin Terre, Thomas Riffelmacher, Roman Pfister   +4 more
wiley   +1 more source

Diffuse large B‐cell lymphoma with phenotype switch, anaplastic features and aberrant T‐cell marker expression during disease evolution

eJHaem, 2022
Xiaoqiong Wang, Pei Lin, Jie Xu, Shaoying Li   +3 more
doaj   +1 more source

Targeting KRAS for cancer therapy

British Journal of Pharmacology, EarlyView.
In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia, Ruonan Liu, Tonia A. Adamide, Isis E. Fernandez, Georgios T. Stathopoulos   +4 more
wiley   +1 more source