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Anaplastic Thyroid Carcinoma [PDF]
Thyroid cancers represent about 1% of all human cancers. Differentiate thyroid carcinomas (DTCs), papillary and follicular cancers, are the most frequent forms, instead Anaplastic Thyroid Carcinoma (ATC) is estimated to comprise 1-2% of thyroid malignancies and it accounts for 14-39% of thyroid cancer deaths. The annual incidence of ATC is about one to
Taccaliti, Augusto +3 more
openaire +4 more sources
How does conformational flexibility influence key structural features involved in activation of anaplastic lymphoma kinase? [PDF]
Anaplastic Lymphoma Kinase (ALK) plays a major role in developing tumor processes and therefore has emerged as a validated therapeutic target. Applying atomistic molecular dynamics simulations on the wild type enzyme and the nine most frequently ...
Lee, Christian +4 more
core +1 more source
Anaplastic thyroid carcinoma: novel therapeutic targets and strategies [PDF]
Anaplastic thyroid carcinoma (ATC) is one of the most aggressive human malignancies, with a mean survival of only 6 months. Therefore, novel therapeutic approaches are desperately required. - dl1520 is a replication competent adenovirus that, due to lack
Libertini, Silvana
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Anaplastic Thyroid Carcinoma: Current Issues in Genomics and Therapeutics
PURPOSE OF REVIEW: Anaplastic thyroid carcinoma is a type of thyroid carcinoma with the most aggressive biological behaviour amongst thyroid cancer. Here, we review the current genomic and the impacts of advances in therapies to improve the management of
Lam, Alfred King-Yin, Abe, Ichiro
core +1 more source
External radiotherapy of thyroid cancer [PDF]
Differentiated thyroid cancer comprises papillary, mixed papillary-follicular and follicular adenocarcinomas. They are mostly hormone-sensitive and respond to thyroid-stimulating hormone (TSH) suppression. The standard treatment is total thyroidectomy. I-
Pollinger, B., Dühmke, Eckhart
core +1 more source
Cardiovascular Involvement of a CD138-Negative Anaplastic Myeloma: A Diagnostic Dilemma
Anaplastic myeloma (AM) is an extremely rare and aggressive histological variant of myeloma. It is characterized by extramedullary presentation in the young and has a poor prognosis. It can be a diagnostic challenge when myeloma is not suspected and even
Jui Choudhuri +5 more
doaj +1 more source
The molecular characterization of poorly and anaplastic thyroid carcinomas has been greatly improved in the last years following the advent of high throughput technologies.
Papotti, Mauro +3 more
core +1 more source
Pictorial Review of Rare Pancreatic Tumors and Tumor-Like Lesions
Various types of tumors and tumor-like lesions may affect the pancreas. Among them, pancreatic ductal adenocarcinoma is the most common and is generally referred to as “pancreatic cancer.” Recently, the detection rates of rare pancreatic tumors and ...
Seung Jae Lee +3 more
doaj +1 more source
Rhabdoid Meningioma: Report of Two Cases [PDF]
Rhabdoid meningioma is an uncommon anaplastic variant of meningioma. We describe the clinicoradiological and histomorphological features of two such cases of meningioma, with a brief review of literature.
Ch. Karunakar Reddy +3 more
doaj +1 more source
Transformation of Mycosis Fungoides/Sezary Syndrome: Clinical Characteristics and Prognosis
Objective: Transformed mycosis fungoides (T-MF) is a rare variant of MF with an aggressive course. In this study, we aimed to describe characteristics of MF/Sezary syndrome (SS) patients with transformation.
Seçil Vural +6 more
doaj +1 more source

