Results 21 to 30 of about 96,938 (286)

Anaplastic Thyroid Carcinoma [PDF]

open access: yesFrontiers in Endocrinology, 2012
Thyroid cancers represent about 1% of all human cancers. Differentiate thyroid carcinomas (DTCs), papillary and follicular cancers, are the most frequent forms, instead Anaplastic Thyroid Carcinoma (ATC) is estimated to comprise 1-2% of thyroid malignancies and it accounts for 14-39% of thyroid cancer deaths. The annual incidence of ATC is about one to
Taccaliti, Augusto   +3 more
openaire   +4 more sources

How does conformational flexibility influence key structural features involved in activation of anaplastic lymphoma kinase? [PDF]

open access: yes, 2014
Anaplastic Lymphoma Kinase (ALK) plays a major role in developing tumor processes and therefore has emerged as a validated therapeutic target. Applying atomistic molecular dynamics simulations on the wild type enzyme and the nine most frequently ...
Lee, Christian   +4 more
core   +1 more source

Anaplastic thyroid carcinoma: novel therapeutic targets and strategies [PDF]

open access: yes, 2008
Anaplastic thyroid carcinoma (ATC) is one of the most aggressive human malignancies, with a mean survival of only 6 months. Therefore, novel therapeutic approaches are desperately required. - dl1520 is a replication competent adenovirus that, due to lack
Libertini, Silvana
core   +2 more sources

Anaplastic Thyroid Carcinoma: Current Issues in Genomics and Therapeutics

open access: yes, 2021
PURPOSE OF REVIEW: Anaplastic thyroid carcinoma is a type of thyroid carcinoma with the most aggressive biological behaviour amongst thyroid cancer. Here, we review the current genomic and the impacts of advances in therapies to improve the management of
Lam, Alfred King-Yin, Abe, Ichiro
core   +1 more source

External radiotherapy of thyroid cancer [PDF]

open access: yes, 2001
Differentiated thyroid cancer comprises papillary, mixed papillary-follicular and follicular adenocarcinomas. They are mostly hormone-sensitive and respond to thyroid-stimulating hormone (TSH) suppression. The standard treatment is total thyroidectomy. I-
Pollinger, B., Dühmke, Eckhart
core   +1 more source

Cardiovascular Involvement of a CD138-Negative Anaplastic Myeloma: A Diagnostic Dilemma

open access: yesHematology Reports, 2023
Anaplastic myeloma (AM) is an extremely rare and aggressive histological variant of myeloma. It is characterized by extramedullary presentation in the young and has a poor prognosis. It can be a diagnostic challenge when myeloma is not suspected and even
Jui Choudhuri   +5 more
doaj   +1 more source

Molecular Pathology of Poorly Differentiated and Anaplastic Thyroid Cancer: What Do Pathologists Need to Know

open access: yes, 2021
The molecular characterization of poorly and anaplastic thyroid carcinomas has been greatly improved in the last years following the advent of high throughput technologies.
Papotti, Mauro   +3 more
core   +1 more source

Pictorial Review of Rare Pancreatic Tumors and Tumor-Like Lesions

open access: yes대한영상의학회지, 2020
Various types of tumors and tumor-like lesions may affect the pancreas. Among them, pancreatic ductal adenocarcinoma is the most common and is generally referred to as “pancreatic cancer.” Recently, the detection rates of rare pancreatic tumors and ...
Seung Jae Lee   +3 more
doaj   +1 more source

Rhabdoid Meningioma: Report of Two Cases [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2015
Rhabdoid meningioma is an uncommon anaplastic variant of meningioma. We describe the clinicoradiological and histomorphological features of two such cases of meningioma, with a brief review of literature.
Ch. Karunakar Reddy   +3 more
doaj   +1 more source

Transformation of Mycosis Fungoides/Sezary Syndrome: Clinical Characteristics and Prognosis

open access: yesTurkish Journal of Hematology, 2018
Objective: Transformed mycosis fungoides (T-MF) is a rare variant of MF with an aggressive course. In this study, we aimed to describe characteristics of MF/Sezary syndrome (SS) patients with transformation.
Seçil Vural   +6 more
doaj   +1 more source

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