Results 71 to 80 of about 125,680 (260)
Anaplastic Thyroid Carcinoma [PDF]
Mayo Clinic Proceedings, 2014 Anaplastic (undifferentiated) thyroid carcinoma is a highly aggressive malignancy that usually presents with a rapidly growing neck mass in older patients, with hoarseness, dysphasia, and vocal cord paralysis. This tumor accounts for 1–2 % of thyroid malignancies.
openaire +2 more sources
Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Advanced Science, EarlyView.Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source
Rare Tumors, 2016 The prognosis of the primary refractory anaplastic lymphoma kinase (ALK+) anaplastic T large cell lymphoma is ominous. The identification of molecular targets with potential to drive oncogenesis remains a cornerstone for the designing of new selective ...
Carolina Valeria Mahuad +5 more
doaj +1 more source
Antibody‐Empowered Nanomedicine for Precise Biomedical Applications
Advanced Science, EarlyView.This review explores strategies for functionalizing nanoparticles with antibodies to construct antibody‐empowered nanomedicine. It discusses the classification of these nanomedicines based on antibody structure, with a specific focus on their biomedical applications in diagnostics, bioimaging, and therapeutics for various diseases.
Chen Chen +7 more
wiley +1 more source
Frontiers in Oncology, 2020 Background: Several previous reports of anaplastic ependymomas have described their imaging features, and most of these studies were case reports. However, no studies have compared the magnetic resonance imaging (MRI) features between the infratentorial ...
Xin-Ping Kuai +5 more
doaj +1 more source
Immunocompetent murine models for the study of glioblastoma immunotherapy. [PDF]
, 2014 Glioblastoma remains a lethal diagnosis with a 5-year survival rate of less than 10%. (NEJM 352:987-96, 2005) Although immunotherapy-based approaches are capable of inducing detectable immune responses against tumor-specific antigens, improvements in ...
Bloch, Orin +9 more
core +2 more sources
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Aim To examine the significance of portal vein tumor thrombus (PVTT) as a prognostic factor for patients with pancreatic ductal adenocarcinoma (PDAC) treated with chemoradiotherapy (CRT) followed by surgery. Methods The study retrospectively examined 313 patients with borderline resectable (BR) or locally advanced (LA) PDAC who underwent CRT ...
Aoi Hayasaki +9 more
wiley +1 more source
Indian Journal of Medical and Paediatric OncologyUndifferentiated (anaplastic) thyroid carcinoma (ATC) is a rare thyroid malignancy, constituting
Aditi Das +4 more
doaj +1 more source
Preoperative Detection of Dual TERT Promoter Mutations in Thyroid Cancer: A Case Series
Diagnostic Cytopathology, EarlyView.ABSTRACT Telomerase reverse transcriptase promoter (TERTp) mutations are associated with aggressive thyroid cancer and are most frequently found in anaplastic and poorly differentiated thyroid cancer. Pre‐operative thyroid nodule molecular testing can detect TERTp, denoting a high risk of malignancy and possible aggressive clinical features such as ...
Amir Harari +7 more
wiley +1 more source
Unmodifiable variables related to thyroid cancer incidence [PDF]
, 2018 The incidence of thyroid cancer is significantly different between male and female patients. Thyroid cancer is also the only form of cancer where age can be considered a staging variable.
Alecu, Lucian +10 more
core +2 more sources