Results 71 to 80 of about 96,938 (286)

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum   +5 more
wiley   +1 more source

Bilateral Symmetry and Variation of Recurrent Laryngeal Nerve and Inferior Thyroid Artery Patterns: An Intraoperative Study of 150 Nerves

open access: yesClinical Anatomy, EarlyView.
ABSTRACT The anatomical relationship of the inferior thyroid artery (ITA) and the recurrent laryngeal nerve (RLN) is highly variable. This study aims to evaluate bilateral RLN branching patterns and their relationship to the ITA within the same patient, predicting contralateral anatomical variations and ultimately reducing intraoperative risk of RLN ...
Mark Yanni   +3 more
wiley   +1 more source

Expression of CD8 is associated with non-common type morphology and outcome in pediatric anaplastic lymphoma kinase-positive anaplastic large cell lymphoma

open access: yesHaematologica, 2013
Anaplastic lymphoma kinase-positive anaplastic large T-cell lymphoma is characterized by morphological variability. Morphological variants (non-common subtype) are associated with a poor outcome.
Dmitriy Abramov   +6 more
doaj   +1 more source

Primary cutaneous anaplastic large-cell lymphoma in a patient with Hodgkin’s disease – case report

open access: yes, 2016
Introduction. Cutaneous anaplastic large cell lymphoma (C-ALCL) is one of the CD30+ lymphoproliferative disorders. Usually it has a mild course and does not require aggressive treatment. The prognosis in C-ALCL is good, with the 10-year survival rate
Dorota Kozłowska   +2 more
core   +1 more source

Efficacy and Safety of Durvalumab and Tremelimumab in Metastatic Non‐Small Cell Lung Cancer: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

open access: yesChronic Diseases and Translational Medicine, EarlyView.
PRISMA 2020 flow diagram of included studies. ABSTRACT Purpose Immune checkpoint inhibitors have transformed treatment strategies for metastatic non‐small cell lung cancer (mNSCLC). This study aimed to assess the efficacy and safety of durvalumab combined with tremelimumab compared with those of standard chemotherapy, particularly in patients with low ...
Ikhwan Rinaldi   +2 more
wiley   +1 more source

ALK (anaplastic lymphoma kinase) [PDF]

open access: yes, 2003
Review on ALK (anaplastic lymphoma kinase), with data on DNA, on the protein encoded, and where the gene is ...
Huret, JL, Senon, S
core   +1 more source

Localizing value of cutaneous ictal phenomena: A systematic review

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective Clinical observation of autonomic signs during seizures can aid in localizing the epileptogenic zone (EZ). We performed a systematic review and meta‐analysis to evaluate the localizing value of ictal cutaneous phenomena—piloerection, sweating, pallor, and flushing—in focal epilepsy and their relevance to presurgical evaluation ...
R. Rocamora   +7 more
wiley   +1 more source

ALK (anaplastic lymphoma kinase) [PDF]

open access: yes, 2001
Review on ALK (anaplastic lymphoma kinase), with data on DNA, on the protein encoded, and where the gene is ...
Huret, JL
core   +1 more source

DNA Methylation and Transcriptomic Profiles of Wilms Tumour Reveal New Deregulated Genes and Epigenetic Processes Relevant for Tumour Stratification and Management

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Wilms Tumour (WT), the most common kidney cancer in children, presents features of altered kidney development and frequently exhibits molecular alterations at the 11p15.5 imprinted locus, affecting the IGF2 and H19 genes, which contribute to tumour growth and predisposition.
Abu Saadat   +14 more
wiley   +1 more source

Multifocal primary cutaneous anaplastic lymphoma

open access: yes, 2016
Primary cutaneous anaplastic large cell lymphoma (CALCL) is a rare lymphoproliferative disorder characterized by proliferation of CD4 T helper cells that express CD30+ marker with anaplastic cytology.
Panthalla Vijaya Lakshmi   +2 more
core   +1 more source

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