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Anaplastic large-cell lymphoma
Seminars in Diagnostic Pathology, 2011The concept of anaplastic large-cell lymphoma (ALCL) has changed over the years because of a stream of new information and novel understanding regarding the cell of origin, biology, genetics, and clinical features of these neoplasms. This new information has led to the current classification proposed by the expert reviewers of the World Health ...
INGHIRAMI, Giorgio +33 more
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Anaplastic large cell lymphoma
Head & Neck, 1991AbstractAnaplastic large cell lymphoma (ALCL) or Ki‐1 lymphoma is a recently described and distinctive non‐Hodgkin's lymphoma. Cervicofacial adenopathy caused by ALCL may mimic involvement by metastatic carcinoma or other malignancies common to the head and neck.
R D, Foss +4 more
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Anaplastic Large Cell Lymphoma
2014Anaplastic large cell lymphoma (ALCL) is a rare lymphoid malignancy that is characterized by the expression of CD30 cell surface receptor and by a chromosomal translocation that results in aberrant constitutive activation of the anaplastic large cell lymphoma kinase (ALK).
Younes A. +3 more
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Large Cell Anaplastic Lymphoma (Ki-1 Lymphoma)
Acta Clinica Belgica, 1992The "large cell anaplastic lymphoma, Ki-1 positive" is a recently described lymphoma subtype (about 1-8% of all NHL). Distinction from Hodgkin's disease and true histiocytic lymphoma/malignant histiocytosis is not always possible, even by experienced pathologists. It was recently incorporated in the updated Kiel Classification of lymphomas.
D, Ebo, A, Van Hoof
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Anaplastic large cell lymphoma
Current Diagnostic Pathology, 2003Abstract Anaplastic large cell lymphoma (ALCL) was first recognized in the 1980s and defined as a distinct clinicopathologic entity based on common histological (pleiomorphic cells) and immunophenotypic (CD30 expression) features. However, neither the presence of pleiomorphic cells nor CD30 positivity proved to be entirely specific, as heterogeneity ...
X Sagaert, C De Wolf-Peeters
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Anaplastic large cell lymphoma
Current Diagnostic Pathology, 1998Anaplastic large cell lymphoma (ALCL) was first recognized in the 1980s and has become recognized as a distinctive clinico-pathologic entity. Morphologically it shows distinctive features including the presence of a characteristic cellular cytology termed by some the ‘hallmark' cell.
K.A. MacLennan, J. Diebold
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Anaplastic lymphoma kinase-negative anaplastic large-cell lymphoma
Egyptian Journal of Dermatology and VenereologyAnaplastic large-cell lymphoma (ALCL) is a non-Hodgkin T-cell lymphoma characterized by persistent expression of CD 30 antigen that represents 2–3% of non-Hodgkin lymphoma (NHL). ALCL may present as a primary cutaneous disease or systemic disease with secondary cutaneous involvement. World Health Organization (WHO) classifies ALCL into ALK-positive and
Shraddha Kote +3 more
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Crizotinib in Anaplastic Large-Cell Lymphoma
New England Journal of Medicine, 2011The anaplastic lymphoma kinase (ALK) inhibitor crizotinib has been shown to induce a response in lung cancers in which ALK is mutated. Crizotinib is also effective in anaplastic large-cell lymphoma, the tumor in which ALK rearrangement was initially detected.
GAMBACORTI PASSERINI, CARLO +2 more
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Anaplastic large cell lymphoma, ALK-positive
Critical Reviews in Oncology/Hematology, 2012Anaplastic large cell lymphoma (ALCL), anaplastic lymphoma kinase (ALK)-positive (ALK+ ALCL) is an aggressive CD30-positive T-cell lymphoma that exhibits a chromosomal translocation involving the ALK gene and the expression of ALK protein. No particular risk factor has been clearly identified for ALCL.
Ferreri AJ +3 more
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Cutaneous intravascular anaplastic large cell lymphoma
Journal of Cutaneous Pathology, 2010Intravascular lymphoma (IL) is a rare variant of non-Hodgkin lymphoma with a predilection for skin. Most reported cases are large B cell lymphomas. Intravascular anaplastic large cell lymphoma (IALCL) is extremely rare. Retrospective analysis of a case of cutaneous IALCL was performed.
Lei, Wang, Chengxin, Li, Tianwen, Gao
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