Anaplastic lymphoma kinase-positive anaplastic large T-cell lymphoma is characterized by morphological variability. Morphological variants (non-common subtype) are associated with a poor outcome.
Dmitriy Abramov +6 more
doaj +1 more source
CD30 - the head of TNF-family… or a successful story of brentuximab vedotin [PDF]
Hodgkin lymphoma and anaplastic large cell lymphoma are malignancies that highly express CD30 antigen on the cell surface. Both are generally curable by standard chemotherapy but refractory diseases and relapses are treatment problems.
Popović Lazar +2 more
doaj +1 more source
Identification and characterization of peripheral T-cell lymphoma-associated SEREX antigens. [PDF]
Peripheral T-cell lymphomas (PTCL) are generally less common and pursue a more aggressive clinical course than B-cell lymphomas, with the T-cell phenotype itself being a poor prognostic factor in adult non-Hodgkin lymphoma (NHL).
Graham P. Collins +34 more
core +2 more sources
Breast Implant-Associated Anaplastic Large Cell Lymphoma (BI-ALCL) [PDF]
Lymphomas are a heterogeneous group of malignant neoplasms constituted by lymphoid cells 1. The occurrence of lymphomas in breast is exceeding rare, but several histotypes have been occasionally reported 2. Breast implant-associated anaplastic large cell
R. Franco, R. Sabetta, A. Ronchi
core +2 more sources
ALK1-Negative Anaplastic Large Cell Lymphoma of the Breast from a Nonprosthesis Cyst
Summary: Anaplastic large cell lymphoma of the breast is a rare malignancy associated with prosthetic breast implants. We present a case of a woman with no prior history of breast implants who developed anaplastic lymphoma kinase-1 negative anaplastic ...
Christopher Mulligan, MBBS +5 more
doaj +1 more source
Primary nodal peripheral T-cell lymphomas: diagnosis and therapeutic considerations
Nodal peripheral T-cell lymphomas are a rare group of neoplasms derived from post-thymic and activated T lymphocytes. A review of scientific articles listed in PubMed, Lilacs, and the Cochrane Library databases was performed using the term "peripheral T ...
Luis Alberto de Pádua Covas Lage +6 more
doaj +1 more source
Coincidence of Anaplastic Lymphoma of the Stomach with Kaposi ’s Sarcoma: A Rare Presentation [PDF]
Anaplastic large-cell lymphoma is an aggressive non-Hodgkin lymphoma of T cell/null cell origin. It rarely affects the gastrointestinal tract. We present the case of a 58-year-old patient diagnosed with anaplastic lymphoma of the stomach in association ...
Sohaila Fatima +2 more
doaj +1 more source
A characteristic feature of anaplastic large cell lymphoma is the significant repression of the T-cell expression program despite its T-cell origin. The reasons for this down-regulation of T-cell phenotype are still unknown.
Maria Joosten +8 more
doaj +1 more source
How does conformational flexibility influence key structural features involved in activation of anaplastic lymphoma kinase? [PDF]
Anaplastic Lymphoma Kinase (ALK) plays a major role in developing tumor processes and therefore has emerged as a validated therapeutic target. Applying atomistic molecular dynamics simulations on the wild type enzyme and the nine most frequently ...
Lee, Christian +4 more
core +1 more source
CD30-positive cutaneous lymphoma: report of four cases with an emphasis on clinicopathological correlations [PDF]
: The classification of cutaneous lymphomas is multidisciplinary and requires the correlation between clinical, histopathological, immunohistochemical, and molecular diagnostic elements. In this article, we present four different cases of CD30-positive T-
Thiago Jeunon de Sousa Vargas +2 more
doaj +2 more sources

