Results 171 to 180 of about 686,182 (220)

A rare case of circulating anaplastic lymphoma kinase-negative anaplastic large cell lymphoma

Hematology, Transfusion and Cell Therapy
Radu Chiriac, Lucile Baseggio
openaire   +4 more sources

Radiotherapy for large ruptured hemorrhagic axillary lymph node metastasis from anaplastic lymphoma kinase-positive lung adenocarcinoma: A case report and review of literature. [PDF]

World J Clin Oncol
Li ZM, Wang YC, Wang KY, Xie NJ, Zhou J, Chang XN, Chen Q, Wang G, Zhang S, Zhou R.   +9 more
europepmc   +1 more source

Anaplastic Lymphoma Kinase-Rearranged Chest Wall-Undifferentiated Small Round Cell Sarcoma With Massive Pleural Effusion and Rapid Progression: A Case With Autopsy Report. [PDF]

Thorac Cancer
Amioka T, Okayasu K, Iwanaga S, Yamamoto M, Tosaka M, Ishikawa T, Kawasaki T, Shimoyama T, Kumagai J.   +8 more
europepmc   +1 more source

Long-term efficacy and improved overall survival of lorlatinib in anaplastic lymphoma kinase-rearranged lung cancer: is cure a dream or a reality? [PDF]

Transl Lung Cancer Res
Horio Y, Kuroda H, Sasaki E, Masago K.
europepmc   +1 more source

Real-world costs, treatment patterns, and clinical outcomes associated with treatments for advanced anaplastic lymphoma kinase-positive non-small cell lung cancer. [PDF]

J Manag Care Spec Pharm
Mudumba R, Liu X, Davis I, Romley JA, Nieva JJ.   +4 more
europepmc   +1 more source

Successful Pregnancies During Crizotinib Therapy for Anaplastic Lymphoma Kinase Positive Lymphoma. [PDF]

Hematol Oncol
Guglielmana V, Fusi FM, Giardini V, Cocito F, Gambacorti-Passerini C.   +4 more
europepmc   +1 more source

Anaplastic Lymphoma Kinase in Cutaneous Malignancies [PDF]

Cancers, 2017
Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase that has been implicated in the pathogenesis of a variety of neoplasms. As suggested by its name, ALK was first described as part of a translocation product in cases of anaplastic large-cell lymphoma, with other genetic and cytogenetic ALK mutations subsequently coming to attention in the ...
Severine Z Cao
exaly   +6 more sources

From Pathology to Precision Medicine in Anaplastic Large Cell Lymphoma Expressing Anaplastic Lymphoma Kinase (ALK+ ALCL)

Cancers, 2017
Anaplastic large cell lymphoma expressing anaplastic lymphoma kinase (ALK+ ALCL) is a distinct subtype of non-Hodgkin lymphoma. In this review, we discuss the historical findings that led to its classification as a unique disease, despite its varied ...
Michael T Werner, Mariusz A Wasik, Michael T Werner   +2 more
exaly   +3 more sources

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Anaplastic lymphoma kinase as a therapeutic target

Expert Opinion on Therapeutic Targets, 2012
Anaplastic lymphoma kinase (ALK), a tyrosine kinase receptor, has been initially identified through its involvement in chromosomal translocations associated with anaplastic large cell lymphoma. However, recent evidence that aberrant ALK activity is also involved in an expanding number of tumor types, such as other lymphomas, inflammatory ...
Laurence Lamant, Camille Laurent, Pierre Brousset   +2 more
exaly   +3 more sources

Anaplastic lymphoma kinase inhibitors

Current Opinion in Pharmacology, 2015
The anaplastic lymphoma kinase (ALK) gene is a member of the insulin receptor superfamily and it has been associated with more than twenty distinct chimera, including established drivers of several human cancers. Multiple clinical trials have proven that the pharmacological inhibition of ALK signaling leads to remarkable clinical improvement and ...
Ramona, Crescenzo, Giorgio, Inghirami
openaire   +2 more sources