Results 141 to 150 of about 96,341 (190)

Influence of the Microbiome on Anastomotic Leak

Clinics in Colon and Rectal Surgery, 2021
AbstractDespite advances in surgical technique and the expanded use of antibiotics, anastomotic leak remains a dreaded complication leading to increased hospital length of stay, morbidity, mortality, and cost. Data continues to grow addressing the importance of a functional and diverse colonic microbiome to ensure adequate healing. Individual pathogens,
Ashley J, Williamson, John C, Alverdy
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Involvement of the Commensal Organism Bacillus subtilis in the Pathogenesis of Anastomotic Leak [PDF]

Surgical Infections, 2020
Background: It is now well established that microbes play a key and causative role in the pathogenesis of anastomotic leak. Yet, in patients, determining whether a cultured pathogen retrieved from an anastomotic leak site is a cause or a consequence of ...
James N Luo, Olga Zaborina
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The Influence of the Microbiome on Anastomotic Leak

Clinics in Colon and Rectal Surgery, 2023
AbstractAnastomotic leak, defined by the International Study Group of Rectal Cancer as “a communication between the intra- and extraluminal compartments owing to a defect of the integrity of the intestinal wall at the anastomosis,” is one of the most devastating complications in colorectal surgery.
Sonja, Boatman, Julia, Kohn, Cyrus, Jahansouz   +2 more
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Management of Acute Anastomotic Leaks

Clinics in Colon and Rectal Surgery, 2021
AbstractManagement of the acute anastomotic leak is complex and patient-specific. Clinically stable patients often benefit from a nonoperative approach utilizing antibiotics with or without percutaneous drainage. Clinically unstable patients or nonresponders to conservative management require operative intervention.
Traci L, Hedrick, William, Kane
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The esophageal anastomotic leak

The American Journal of Surgery, 1976
Sixty-three esophageal anastomoses were performed on adult patients with esophageal or gastric cancer. A total of thirteen anastomotic leaks occurred, resulting in death in seven patients and serious morbidity in an additional patients. Twelve patients had esophagocolostomy, with five anastomotic leaks.
A S, Hermreck, D G, Crawford
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Endoluminal Suturing of an Anastomotic Leak

The Annals of Thoracic Surgery, 2015
An anastomotic leak can be one of the most morbid and complex complications after esophagectomy. Typically, management can entail repair, stenting, or diversion. The leak complicates a patient's postoperative course and delays initiation of any adjuvant therapy.
Puja, Gaur, Calvin, Lyons, Tayyaba M, Malik, Min P, Kim, Shanda H, Blackmon   +4 more
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Anastomotic leak after surgery for colon cancer and effect on long‐term survival [PDF]

Colorectal Disease, 2020
Aim An anastomotic leak after surgery for colon cancer is a recognized complication but how it may adversely affect long‐term survival is less clear because data are scarce.
Kjartan Stormark, Andreas Nordholm-Carstensen   +1 more
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Radiographic Findings of Anastomotic Leaks

The American Surgeon™, 2013
Although computed tomography (CT) scans play an important role in the diagnosis and management of anastomotic leaks (AL), there is no consensus on what radiographic findings are associated with AL. The purpose of this study is to identify the most common CT scan findings associated with AL and whether the amount of extraluminal air or the density of ...
Elizabeth T, Lynn, Julia, Chen, Eric J, Wilck, Kerri, El-Sabrout, Chris C, Lo, Celia M, Divino   +5 more
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Diagnosis and Management of Chronic Anastomotic Leak

Clinics in Colon and Rectal Surgery, 2021
AbstractChronic anastomotic leaks present a daunting challenge to colorectal surgeons. Unfortunately, anastomotic leaks are common, and a significant number of leaks are diagnosed in a delayed fashion. The clinical presentation of these chronic leaks can be silent or have low grade, indolent symptoms.
Anuradha R, Bhama, Justin A, Maykel
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Anastomotic Leak After Esophagectomy

Thoracic Surgery Clinics, 2006
Anastomotic leaks continue to be a source of considerable morbidity and mortality after esophageal resection. Careful attention to the contributing factors to the development of a leak, particularly conduit ischemia and anastomotic technique, can reduce the incidence of anastomotic complications postoperatively. Selective management of leaks, including
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