Comparative genetics of Enterococcus faecalis intestinal tissue isolates before and after surgery in a rat model of colon anastomosis. [PDF]
, 2020 We have recently demonstrated that collagenolytic Enterococcus faecalis plays a key and causative role in the pathogenesis of anastomotic leak, an uncommon but potentially lethal complication characterized by disruption of the intestinal wound following ...
Alverdy, John C +8 more
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The Esophagogastric Anastomosis
Annals of Surgery Open, 2023 Background:. The incidence of anastomotic leakage in gastrointestinal surgery is highest after esophagogastric anastomosis, with leakage rates of 10% to 38% still being reported, but little consensus as to cause or corrective.
Thomas N. Walsh, FRCSI
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STAPLED VERSUS HANDSEWN INTESTINAL ANASTOMOSIS IN EMERGENCY SURGERY
Basrah Journal of Surgery, 2022 The major problem following bowel anastomoses is the anastomotic failure leading to leakage peritonitis, fistula, abscess, sepsis, necrosis, stricture etc. adding to the morbidity and mortality. (e.g., 22% mortality in patients with a leak vs.
Mebin Mathew +2 more
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Reducing gastrointestinal anastomotic leak rates: Review of challenges and solutions [PDF]
, 2016 Various techniques and interventions have been developed in an effort to obviate gastrointestinal anastomotic leaks. This review is intended to delineate potential modifications that can be made to reduce the risk of anastomotic leaks following ...
Philllips, Benjamin
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Short-term outcomes of Ivor Lewis vs. McKeown esophagectomy: A meta-analysis
Frontiers in Surgery, 2022 ObjectiveThe objective of this article is to assess the rate of anastomotic leak and other perioperative outcomes in patients undergoing esophagectomy with either thoracic or cervical anastomosis.MethodsThis meta-analysis was conducted by searching ...
Huajie Xing +3 more
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JTCVS Open, 2021 Objective: Esophagectomy remains the mainstay of treatment for nonmetastatic esophageal cancer. The optimal technique for anastomosis after esophagectomy remains unknown.
Tommi Järvinen, MD, PhD +4 more
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Meta‐analysis of oral antibiotics, in combination with preoperative intravenous antibiotics and mechanical bowel preparation the day before surgery, compared with intravenous antibiotics and mechanical bowel preparation alone to reduce surgical‐site infections in elective colorectal surgery [PDF]
, 2018 Background: Surgical‐site infection (SSI) is a potentially serious complication following colorectal surgery. The present systematic review and meta‐analysis aimed to investigate the effect of preoperative oral antibiotics and mechanical bowel ...
McMahon, A.J. +2 more
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Journal of Cardiothoracic Surgery, 2019 Background Minimally invasive McKeown esophagectomy is an important surgical approach for esophageal cancer. Anastomotic leak is one of its common and serious complications. We assumed that the preoperative risk factors and postoperative indicators would
Chuan Gao +3 more
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Multicentre observational cohort study of NSAIDs as risk factors for postoperative adverse events in gastrointestinal surgery [PDF]
, 2014 Introduction: Non-steroidal anti-inflammatory drugs (NSAIDs) are recommended as postoperative analgesia by the Enhanced Recovery After Surgery Society. Recent studies have raised concerns that NSAID administration following colorectal anastomosis may be ...
Bhangu, A +6 more
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The relationship between systemic inflammation and stoma formation following anterior resection for rectal cancer: a cross-sectional study [PDF]
, 2017 Introduction: There is evidence that temporary defunctioning stoma formation in patients undergoing anterior resection reduces the risk of anastomotic leakage.
Horgan, Paul G. +3 more
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