Results 101 to 110 of about 530,420 (288)

BRCA1 Mutation‐Recognizing Tetrahedral Framework Nucleic Acid Nanoplatform Enables Coordinated PARP/WEE1 Inhibition and STING‐Associated Antitumor Immunity in Ovarian Cancer

Advanced Science, EarlyView.
BRCA1 mutation‐responsive FBOA‐tFNA selectively recognizes mutant transcripts and coordinates reduction‐responsive intracellular delivery of olaparib and adavosertib, amplifying DNA damage and weakening G2/M checkpoint protection. These effects are accompanied by STING‐associated immune activation and stronger antitumor immunity, while sequential anti ...
Chenyi Wang, Mengying Yao, Jinhui Xie, Dingjie Wang, Yashi Shi, Xiaodan Mao, Chunhua Lu, Pengming Sun   +7 more
wiley   +1 more source

Stroke‐Heart Syndrome: Mechanisms, Temporal Phenotypes, and Diagnostic Reasoning

Advanced Science, EarlyView.
Stroke‐heart syndrome describes new or worsened cardiac abnormalities after acute stroke. This Review defines its clinical boundaries, traces autonomic, inflammatory, endothelial, and supply‐demand mechanisms across time, and proposes provisional phenotypes that integrate lesion location, premorbid cardiac substrate, serial biomarkers ...
Fa Lin, Jian Lyu, Yanci Liu, Zhiyuan Feng, Jie Bao, Wenxiong Song, Bingcheng Zhu, Minghao Liu, Jionghao Xue, Jiadi Weng, Jiani Zhang, Jizong Zhao, Xiaolin Chen, Bin Dong   +13 more
wiley   +1 more source

Anatomical relationship between maxillary posterior teeth and the maxillary sinus in an Indonesian population: a CT scan study

BMC Oral Health
Background The anatomical proximity between the root apex of the maxillary posterior teeth and the maxillary sinus can lead to complications, including odontogenic maxillary sinusitis.
Erli Sarilita, Rizky Maulana Muhammad, Harry Galuh Nugraha, Nani Murniati, Harmas Yazid Yusuf, Yohei Takeshita, Junichi Asaumi   +6 more
doaj   +1 more source

Church Minutes Volume 12, 1979-1984 (Apex Baptist Church, Apex, NC)

Church Minutes Volume 12, 1979-1984 (Apex Baptist Church, Apex ...

core   +1 more source

Mac‐2 Binding Protein Glycosylation Isomer (M2BPGi)–Based Risk Stratification Refined by Tumor Metabolic Activity in Hepatocellular Carcinoma

Annals of Gastroenterological Surgery, EarlyView.
M2BPGi reflects background liver fibrosis and hepatic functional impairment. PET SUVmax reflects tumor metabolic aggressiveness. Their combination identifies a dual‐high subgroup with the poorest recurrence‐free and overall survival. ABSTRACT Aim To evaluate the prognostic significance of preoperative Mac‐2 binding protein glycosylation isomer (M2BPGi)
Kojiro Shirabe, Junya Mita, Shinji Itoh, Takeo Toshima, Yoshiyuki Kitamura, Norifumi Iseda, Takuro Isoda, Kousei Ishigami, Tomoharu Yoshizumi   +8 more
wiley   +1 more source

Historical Development and Applications of the EPIC and APEX Models, June 2005 [PDF]

, 2005
The development of the field-scale Erosion Productivity Impact Calculator (EPIC) model was initiated in 1981 to support assessments of soil erosion impacts on soil productivity for soil, climate, and cropping conditions representative of a broad ...

core  

Spatially Informed Feature Selection and Machine Learning in Matrix‐Assisted Laser Desorption/Ionization Imaging for Cohort‐Scale Molecular Tissue Phenomics in Glioblastoma

Advanced Intelligent Discovery, EarlyView.
Matrix‐assisted laser desorption/ionization imaging‐based identification of reliable small molecule markers across heterogeneous glioblastoma cohorts is challenging with intensity‐only methods. We present spatially informed feature selection (SIFS), a spatially informed framework that prioritizes molecules consistently colocalizing with histopathology.
Shad A. Mohammed, Denis Abu Sammour, Dirk C. Hoffmann, Philipp Sievers, Tobias Bausbacher, Melissa Hahn, Yasemin Ucal, Iris Mildenberger, Christiane A. Opitz, Stefan Schmidt, Michael Platten, Oliver Wasenmüller, Wolfgang Wick, Andreas von Deimling, Tobias Kessler, Carsten Hopf   +15 more
wiley   +1 more source

Proximity of maxillary molar palatal roots to adjacent structures for endodontic microsurgery: a cone-beam computed tomography study

BMC Oral Health
Background The surgical complexity associated with the palatal roots of maxillary molars was considerably elevated. Previous studies on the relationships between maxillary molar roots and the maxillary sinus or cortical plates have focused on individual ...
Xiaoxiang Huang, Jun Xu, Benxiang Hou, Ying Wang   +3 more
doaj   +1 more source

A Cable‐Driven Parallel Wire Robot for Probe Positioning and Tissue Palpation on Curved Phantoms

Advanced Intelligent Systems, EarlyView.
A wearable cable‐driven parallel robot is introduced for autonomous ultrasound probe positioning and soft tissue palpation on curved surfaces. By combining visual feedback with tension‐optimized control, the system achieves millimeter‐scale positioning accuracy while enforcing safety force constraints.
Christina Patterson, Dinesh K. Patel, Carmel Majidi   +2 more
wiley   +1 more source

APEX ORGANIZATIONS AND THE GROWTH OF MICROFINANCE IN BOLIVIA [PDF]

Bolivia has the most advanced microfinance sector in Latin America and has been a model worldwide. Apex banks banks that lend to banks have not been responsible for this success.
Navajas, Sergio, Schreiner, Mark
core   +2 more sources