Results 41 to 50 of about 530,420 (288)

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

open access: yesAdvanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang   +12 more
wiley   +1 more source

Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing

open access: yesAdvanced Science, EarlyView.
Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley   +1 more source

Morphological and morphometric analysis of the sacral hiatus using lumbosacral spine CT scans: clinical relevance in caudal epidural analgesia

open access: yesFolia Morphologica
BACKGROUND: To conduct a morphological and morphometric analysis of the sacral hiatus (SH) using lumbosacral spine CT scans and to evaluate its clinical relevance in caudal epidural analgesia (CEA).
Apurba Patra   +9 more
doaj   +1 more source

A review of the relation between peripheral anatomical structures and external apical root resorption during orthodontic treatment [PDF]

open access: yesKouqiang yixue
External apical root resorption(EARR)is one of the most common side effects of orthodontic treatment. Contact with surrounding anatomical structures during tooth movement is a significant cause for EARR. However, a comprehensive review of factors leading
CHEN Ziang, LIU Ziang, OUYANG Yuqing, LOU Yiting, SHI Jiejun, DING Wanghui
doaj   +1 more source

Anatomical and morphometric study of optic foramen in North Indian population

open access: yesNational Journal of Clinical Anatomy, 2019
Introduction Optic canal connects orbit to middle cranial fossa. Optic nerve and ophthalmic artery pass through this canal. The aim of the present study is to make morphometric and anatomical observations of endocranial opening of optic canal. Materials
Ajay Kumar   +6 more
doaj   +1 more source

The influence of the maxillary sinus on maxillary posterior tooth endodontic microsurgery

open access: yes口腔疾病防治, 2022
Endodontic microsurgery is one effective method for preserving teeth affected by periapical disease, and is also an essential technique for treating difficult cases.
SUN Mingxin   +2 more
doaj   +1 more source

SemanticST: A Scalable Multi‐Contextual Graph Learning Framework for Uncovering Spatial Niches and Robust Multi‐Sample Integration in Spatial Transcriptomics

open access: yesAdvanced Science, EarlyView.
Technical limitations often let dominant signals overshadow rare cell types and fine‐grained heterogeneity in spatial transcriptomics. SemanticST, a graph neural network using multi‐semantic graph fusion and a novel min‐cut loss, recovers these subtle patterns.
Roxana Zahedi   +7 more
wiley   +1 more source

Three-dimensional morphological analysis of the thoracic pedicle and related radiographic factors in adolescent idiopathic scoliosis

open access: yesBMC Musculoskeletal Disorders, 2022
Background This study aimed to investigate the laterality of the pedicle morphology at the apical vertebra (AV) level and identify the radiographic factors associated with the laterality ratio of the pedicle morphology at the AV level in patients with ...
Tatsuya Sato   +10 more
doaj   +1 more source

Arrayed Magnetic Accelerator Synergistically Enhances Orthodontic Tooth Movement via Microtubule Assembly‐Mediated Periodontal Remodeling

open access: yesAdvanced Science, EarlyView.
Mechanical orthodontic treatment for malocclusion is limited by slow remodeling and risks due to poor biomechanical sensing. This study shows that static magnetic fields (SMFs) enhance mechanical sensation in periodontal ligament cells, promoting inflammation and osteoclast activity.
Yiling Lou   +11 more
wiley   +1 more source

Enteric ChAT‐Expressing Neurons Mediate the Protective Effect of Lactobacillus plantarum in Inflammatory Bowel Disease

open access: yesAdvanced Science, EarlyView.
In colitis patients and mice, reduced Lactobacillus abundance is observed. Experimental studies show that L. plantarum A736 metabolizes dietary tryptophan into indole‐3‐lactic acid (ILA), while both L. plantarum A736 and ILA impact ChAT‐expressing enteric neurons and acetylcholine levels, thereby regulating intestinal immune responses and alleviating ...
Bing Xia   +15 more
wiley   +1 more source

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