Correlative Imaging Platform Linking Taste Cell Function to Molecular Identity
A correlative imaging platform is developed to study how individual taste cells respond to different taste qualities. By linking cellular activity with molecular identity and environmental context, dual‐tuned taste cells capable of detecting both sweet and umami stimuli are identified.
Sungho Lee +6 more
wiley +1 more source
Insulin-mediated synaptic plasticity in the CNS: Anatomical, functional and temporal contexts
Carrie R. Ferrario, Lawrence P. Reagan
openalex +1 more source
Transplantation of medial ganglionic eminence (MGE) interneuron progenitors into APP/PS1 cortices restored the slow oscillation characteristic of Alzheimer's disease. Donor cells survived, migrated, and matured into functional GABAergic interneurons, forming synaptic connections.
Shinya Yokomizo +16 more
wiley +1 more source
A Virtual Clinical Trial of Psychedelics to Treat Patients With Disorders of Consciousness
Disorders of consciousness after severe brain injury are marked by reduced complexity of brain activity and limited treatment options. Using personalized whole‐brain models, this study shows that simulated lysergic acid diethylamide (LSD) and psilocybin shift patient brain dynamics closer to criticality.
Naji L.N. Alnagger +17 more
wiley +1 more source
D-Serine's Journey Between Stars and Synapses. [PDF]
Mountadem S, Oliet SHR, Panatier A.
europepmc +1 more source
Rigid Hollow Microparticles for Enhanced Focused Ultrasound Treatment Under Optoacoustic Guidance
By combining focused ultrasound (FUS) and acoustically active hollow borosilicate microparticles (HBMPs), we demonstrate tunable control over interparticle dynamics and their localized thermal energy deposition. Modulation of acoustic frequency and particle concentration tailors the energy delivery, allowing adaptive, material‐based regulation of ...
Nima Mahkam +6 more
wiley +1 more source
The Role of Ion Channels and Transporters in Human Health and Diseases. [PDF]
Soda T.
europepmc +1 more source
Neural plasticity in functional and anatomical MRI studies of children with Tourette syndrome.
Heike Eichele, Kerstin Jessica Plessen
openalex +2 more sources
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong +6 more
wiley +1 more source
Response to letter regarding 'local large arterial perivascular adipose tissue metabolic and anatomical features are associated with hypertensive clinical outcomes: a PET/CT-Based study'. [PDF]
Long HY, Chen GD, Chen BQ.
europepmc +1 more source

