Results 1 to 10 of about 110,433 (337)

Physiological evidence consistent with reduced neuroplasticity in human adolescents born preterm [PDF]

open access: bronze, 2012
Preterm-born children commonly experience motor, cognitive, and learning difficulties that may be accompanied by altered brain microstructure, connectivity, and neurochemistry.
Clow, A.   +19 more
core   +3 more sources

Neuroplasticity

open access: yesBelügyi Szemle, 2021
As editor Bruce Tidor sets it in the preface of the book, published in the volume of the MIT Essential Knowledge series: ‘Synthesizing specialized subject matter for non-specialists and engaging critical topics through fundamentals, each of these compact volumes offers readers a point of access to complex ideas.’ (Costandi, 2016).
Howard Burton, Greg Hickok
  +7 more sources

Neuroplasticity [PDF]

open access: yes, 2013
Montagut Bordas, Carlota   +1 more
core   +5 more sources

The nuclear lamina is a hub for the nuclear function of Jacob

open access: yesMolecular Brain, 2021
Jacob is a synapto-nuclear messenger protein that couples NMDAR activity to CREB-dependent gene expression. In this study, we investigated the nuclear distribution of Jacob and report a prominent targeting to the nuclear envelope that requires NMDAR ...
Sebastian Samer   +4 more
doaj   +1 more source

Neddylation-dependent protein degradation is a nexus between synaptic insulin resistance, neuroinflammation and Alzheimer’s disease

open access: yesTranslational Neurodegeneration, 2022
Background The metabolic syndrome is a consequence of modern lifestyle that causes synaptic insulin resistance and cognitive deficits and that in interaction with a high amyloid load is an important risk factor for Alzheimer's disease.
Alessandro Dario Confettura   +12 more
doaj   +1 more source

A Jacob/nsmf gene knockout does not protect against acute hypoxia- and NMDA-induced excitotoxic cell death

open access: yesMolecular Brain, 2023
Jacob is a synapto-nuclear messenger protein that encodes and transduces the origin of synaptic and extrasynaptic NMDA receptor signals to the nucleus. The protein assembles a signalosome that differs in case of synaptic or extrasynaptic NMDAR activation.
Guilherme M. Gomes   +3 more
doaj   +1 more source

Mitochondria and Neuroplasticity [PDF]

open access: yesASN Neuro, 2010
The production of neurons from neural progenitor cells, the growth of axons and dendrites and the formation and reorganization of synapses are examples of neuroplasticity. These processes are regulated by cell-autonomous and intercellular (paracrine and endocrine) programs that mediate responses of neural cells to environmental input.
Aiwu Cheng, Yan Hou, Mark P Mattson
openaire   +3 more sources

Short high fat diet triggers reversible and region specific effects in DCX+ hippocampal immature neurons of adolescent male mice

open access: yesScientific Reports, 2021
Adolescence represents a crucial period for maturation of brain structures involved in cognition. Early in life unhealthy dietary patterns are associated with inferior cognitive outcomes at later ages; conversely, healthy diet is associated with better ...
Fausto Chiazza   +6 more
doaj   +1 more source

An updated suite of viral vectors for in vivo calcium imaging using intracerebral and retro-orbital injections in male mice

open access: yesNature Communications, 2023
Genetically encoded Ca2+ indicators (GECIs) are used to measure neural activity. Here, authors screen GECI constructs for suitability with systemic injections and soma-targeting, and modify a soma-targeting peptide for improved expression rate.
Sverre Grødem   +6 more
doaj   +1 more source

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