Results 1 to 10 of about 53,810 (159)
Belügyi Szemle, 2021 As editor Bruce Tidor sets it in the preface of the book, published in the volume of the MIT Essential Knowledge series: ‘Synthesizing specialized subject matter for non-specialists and engaging critical topics through fundamentals, each of these compact volumes offers readers a point of access to complex ideas.’ (Costandi, 2016).
Howard Burton, Greg Hickok
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The nuclear lamina is a hub for the nuclear function of Jacob
Molecular Brain, 2021 Jacob is a synapto-nuclear messenger protein that couples NMDAR activity to CREB-dependent gene expression. In this study, we investigated the nuclear distribution of Jacob and report a prominent targeting to the nuclear envelope that requires NMDAR ...
Sebastian Samer +4 more
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Translational Neurodegeneration, 2022 Background The metabolic syndrome is a consequence of modern lifestyle that causes synaptic insulin resistance and cognitive deficits and that in interaction with a high amyloid load is an important risk factor for Alzheimer's disease.
Alessandro Dario Confettura +12 more
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Molecular Brain, 2023 Jacob is a synapto-nuclear messenger protein that encodes and transduces the origin of synaptic and extrasynaptic NMDA receptor signals to the nucleus. The protein assembles a signalosome that differs in case of synaptic or extrasynaptic NMDAR activation.
Guilherme M. Gomes +3 more
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Mitochondria and Neuroplasticity [PDF]
ASN Neuro, 2010 The production of neurons from neural progenitor cells, the growth of axons and dendrites and the formation and reorganization of synapses are examples of neuroplasticity. These processes are regulated by cell-autonomous and intercellular (paracrine and endocrine) programs that mediate responses of neural cells to environmental input.
Aiwu Cheng, Yan Hou, Mark P Mattson
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Scientific Reports, 2021 Adolescence represents a crucial period for maturation of brain structures involved in cognition. Early in life unhealthy dietary patterns are associated with inferior cognitive outcomes at later ages; conversely, healthy diet is associated with better ...
Fausto Chiazza +6 more
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Nature Communications, 2023 Genetically encoded Ca2+ indicators (GECIs) are used to measure neural activity. Here, authors screen GECI constructs for suitability with systemic injections and soma-targeting, and modify a soma-targeting peptide for improved expression rate.
Sverre Grødem +6 more
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Brain Sciences, 2021 Recent technological advances have been permitted to use high-density electroencephalography (hdEEG) for the estimation of functional connectivity and the mapping of resting-state networks (RSNs).
Gaia Amaranta Taberna +3 more
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Context value updating and multidimensional neuronal encoding in the retrosplenial cortex
Nature Communications, 2021 Goal-directed behaviors require the brain to integrate information across many task-related dimensions. Here, the authors use a virtual context discrimination paradigm in mice to demonstrate the capacity for neurons in the retrosplenial cortex to exhibit
Weilun Sun +7 more
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Cells, 2022 Understanding changes in the expression of genes involved in regulating various components of the neural extracellular matrix (ECM) during aging can provide an insight into aging-associated decline in synaptic and cognitive functions.
David Baidoe-Ansah +8 more
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