Results 11 to 20 of about 73,223 (297)

Mitochondria and Neuroplasticity [PDF]

open access: yesASN Neuro, 2010
The production of neurons from neural progenitor cells, the growth of axons and dendrites and the formation and reorganization of synapses are examples of neuroplasticity. These processes are regulated by cell-autonomous and intercellular (paracrine and endocrine) programs that mediate responses of neural cells to environmental input.
Aiwu Cheng, Yan Hou, Mark P Mattson
openaire   +4 more sources

Neuroplasticity and psychiatry

open access: yesAustralian and New Zealand Journal of Psychiatry, 1998
Objective: There is increasing concern that the course of psychiatric disorders may be affected by parameters such as the duration and intensity of symptoms of initial episodes of illness. As this indicates that abnormal function produces long-term changes within the brain, a review of the neuroscience literature regarding neuroplasticity is warranted.
Gynther, BD, Calford, MB, Sah, P
openaire   +6 more sources

Conrad’s Neuroplasticity

open access: yesModernism/modernity, 2016
“Our brain is plastic and we do not know it” says French philosopher Catherine Malabou. This article argues that Joseph Conrad knew it. In the process it suggests that contemporary discoveries in the neurosciences about the “neuroplasticity” of the human brain can be supplemented by tracing the aesthetic and conceptual implications of the plastic ...
Lawtoo, N., Lawtoo, Nidesh
openaire   +3 more sources

Neuroplasticity and Alzheimer’s Disease [PDF]

open access: yesJournal of Integrative Neuroscience
Alzheimer’s disease (AD) is a progressive neurodegenerative disease that leads to a decline in cognitive function, including memory. The exact causes of AD are not fully understood, and to date no treatments are available that can stop the progression of this neurocognitive disorder.
Ashkan Asgari Gashtrodkhani   +6 more
openaire   +4 more sources

The nuclear lamina is a hub for the nuclear function of Jacob

open access: yesMolecular Brain, 2021
Jacob is a synapto-nuclear messenger protein that couples NMDAR activity to CREB-dependent gene expression. In this study, we investigated the nuclear distribution of Jacob and report a prominent targeting to the nuclear envelope that requires NMDAR ...
Sebastian Samer   +4 more
doaj   +1 more source

Gut Microbiota and Neuroplasticity [PDF]

open access: yesCells, 2021
The accumulating evidence linking bacteria in the gut and neurons in the brain (the microbiota–gut–brain axis) has led to a paradigm shift in the neurosciences. Understanding the neurobiological mechanisms supporting the relevance of actions mediated by the gut microbiota for brain physiology and neuronal functioning is a key research area.
Julia Murciano-Brea   +3 more
openaire   +4 more sources

Neddylation-dependent protein degradation is a nexus between synaptic insulin resistance, neuroinflammation and Alzheimer’s disease

open access: yesTranslational Neurodegeneration, 2022
Background The metabolic syndrome is a consequence of modern lifestyle that causes synaptic insulin resistance and cognitive deficits and that in interaction with a high amyloid load is an important risk factor for Alzheimer's disease.
Alessandro Dario Confettura   +12 more
doaj   +1 more source

Short high fat diet triggers reversible and region specific effects in DCX+ hippocampal immature neurons of adolescent male mice

open access: yesScientific Reports, 2021
Adolescence represents a crucial period for maturation of brain structures involved in cognition. Early in life unhealthy dietary patterns are associated with inferior cognitive outcomes at later ages; conversely, healthy diet is associated with better ...
Fausto Chiazza   +6 more
doaj   +1 more source

A Jacob/nsmf gene knockout does not protect against acute hypoxia- and NMDA-induced excitotoxic cell death

open access: yesMolecular Brain, 2023
Jacob is a synapto-nuclear messenger protein that encodes and transduces the origin of synaptic and extrasynaptic NMDA receptor signals to the nucleus. The protein assembles a signalosome that differs in case of synaptic or extrasynaptic NMDAR activation.
Guilherme M. Gomes   +3 more
doaj   +1 more source

An updated suite of viral vectors for in vivo calcium imaging using intracerebral and retro-orbital injections in male mice

open access: yesNature Communications, 2023
Genetically encoded Ca2+ indicators (GECIs) are used to measure neural activity. Here, authors screen GECI constructs for suitability with systemic injections and soma-targeting, and modify a soma-targeting peptide for improved expression rate.
Sverre Grødem   +6 more
doaj   +1 more source

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