Results 1 to 10 of about 841,514 (309)

A longitudinal, randomized experimental pilot study to investigate the effects of airborne infrasound on human mental health, cognition, and brain structure

open access: yesScientific Reports, 2021
Airborne infrasound (IS; emitted by e.g., large machinery, wind farms) is ubiquitous in technologized environments. Health hazards are controversially discussed at present.
L. Ascone   +4 more
doaj   +1 more source

Why do mice squeak? Toward a better understanding of defensive vocalization

open access: yesiScience, 2022
Summary: Although mice mostly communicate in the ultrasonic range, they also emit audible calls. We demonstrate that mice selectively bred for high anxiety-related behavior (HAB) have a high disposition for emitting sonic calls when caught by the tail ...
Julia Ruat   +7 more
doaj   +1 more source

Unique potential of immature adult-born neurons for the remodeling of CA3 spatial maps

open access: yesCell Reports, 2023
Summary: Mammalian hippocampal circuits undergo extensive remodeling through adult neurogenesis. While this process has been widely studied, the specific contribution of adult-born granule cells (aGCs) to spatial operations in the hippocampus remains ...
Matías Mugnaini   +4 more
doaj   +1 more source

Olfactory bulb plasticity ensures proper olfaction after severe impairment in postnatal neurogenesis

open access: yesScientific Reports, 2017
The olfactory bulb (OB) neurons establish a complex network that ensures the correct processing of the olfactory inputs. Moreover, the OB presents a lifelong addition of new neurons into its existing circuitry.
D. Díaz   +5 more
doaj   +1 more source

Diverse processing of pharmacological and natural rewards by the central amygdala

open access: yesCell Reports, 2023
Summary: The central amygdala (CeA) with its medial (CeM) and lateral (CeL) nuclei is the brain hub for processing stimuli with emotional context. CeL nucleus gives a strong inhibitory input to the CeM, and this local circuitry assigns values (positive ...
Łukasz Bijoch   +5 more
doaj   +1 more source

Click Chemistry (CuAAC) and Detection of Tagged de novo Synthesized Proteins in Drosophila

open access: yesBio-Protocol, 2019
Copper-catalyzed azide-alkyne-cycloaddition (CuAAC), also known as ‘click chemistry’ serves as a technique for bio-orthogonal, that is, bio-compatible labeling of macromolecules including proteins or lipids.
Kathrin Marter   +8 more
doaj   +1 more source

Birdsongs alleviate anxiety and paranoia in healthy participants

open access: yesScientific Reports, 2022
The present study investigated the effect of urban (traffic noise) vs. natural (birdsongs) soundscapes on mood, state paranoia, and cognitive performance, hypothesizing that birdsongs lead to significant improvements in these outcomes. An additional goal
E. Stobbe   +3 more
doaj   +1 more source

Soluble Ectodomain of Neuroligin 1 Decreases Synaptic Activity by Activating Metabotropic Glutamate Receptor 2

open access: yesFrontiers in Molecular Neuroscience, 2017
Synaptic cell adhesion molecules represent important targets for neuronal activity-dependent proteolysis. Postsynaptic neuroligins (NLs) form trans-synaptic complexes with presynaptic neurexins (NXs). Both NXs and NLs are cleaved from the cell surface by
Michelle D. Gjørlund   +9 more
doaj   +1 more source

Melatonin Reduces NLRP3 Inflammasome Activation by Increasing α7 nAChR-Mediated Autophagic Flux

open access: yesAntioxidants, 2020
Microglia controls the immune system response in the brain. Specifically, the activation and dysregulation of the NLRP3 inflammasome is responsible for the initiation of the inflammatory process through IL-1β and IL-18 release.
Víctor Farré-Alins   +13 more
doaj   +1 more source

Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Protects Striatal Cells and Improves Motor Function in Huntington’s Disease Models: Role of PAC1 Receptor

open access: yesFrontiers in Pharmacology, 2022
Huntington’s disease (HD) is a hereditary neurodegenerative disorder caused by the expression of mutant huntingtin (mHtt). One of the main features of HD is the degeneration of the striatum that leads to motor discoordination. Pituitary adenylate cyclase-
Irene Solés-Tarrés   +11 more
doaj   +1 more source

Home - About - Disclaimer - Privacy