THE FUNDAMENTS OF NEURONAL PLASTICITY
Plasticity of the nervous system is determined by the modification of efficacy of synaptic transmission: long- term potentiation and long- term depression. Different modern technical approaches such as: registration of ionic currents in single neuron, molecular- genetic analysis, neurovisualization, and others reveal the molecular mechanisms of ...
V G, Skrebitskiĭ, M B, Shtark
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Structural plasticity of synaptic connectivity in the adult hippocampal mossy fiber projection [PDF]
The brain has the lifelong ability to change itself based on new experiences such as learning and memory. This so called neuronal plasticity is reflected in the brain by structural and functional modifications which underlie our ability to learn ...
Ruediger, Sarah
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Network self-organization explains the statistics and dynamics of synaptic connection strengths in cortex [PDF]
The information processing abilities of neural circuits arise from their synaptic connection patterns. Understanding the laws governing these connectivity patterns is essential for understanding brain function.
Jochen Triesch (106561) +13 more
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Neuronal plasticity and antidepressant actions [PDF]
Antidepressant treatments enhance plasticity and increase neurogenesis in the adult brain, but it has been unclear how these effects influence mood. We propose that, like environmental enrichment and exercise, antidepressant treatments enhance adaptability by increasing structural variability within the nervous system at many levels, from proliferating
Eero, Castrén, René, Hen
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Preconditioning of low-frequency repetitive transcranial magnetic stimulation with transcranial direct current stimulation: evidence for homeostatic plasticity in the human motor cortex [PDF]
Recent experimental work in animals has emphasized the importance of homeostatic plasticity as a means of stabilizing the properties of neuronal circuits. Here, we report a phenomenon that indicates a homeostatic pattern of cortical plasticity in healthy
Siebner, H.R. +11 more
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Neuronal Plasticity and Function
Neuronal plasticity is a key issue in neuroscience. It is defined as the capability of the neuron to adapt to a changing internal or external environment, to previous experience or to trauma. It appears that during all phases of the individual life span in the nervous system, changes take place that relate to development, degeneration, and regeneration.
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The function of Copine 6 in the brain [PDF]
The formation of new or the remodeling of pre-existing synapses is thought to provide the cellular correlate of learning and memory processes. In the mammalian forebrain, the postsynaptic site of most excitatory synapses is located on dendritic spines ...
Reinhard, Judith
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Oligodendrocytes and myelin limit neuronal plasticity in visual cortex. [PDF]
Developmental myelination is a protracted process in the mammalian brain1. One theory for why oligodendrocytes mature so slowly posits that myelination may stabilize neuronal circuits and temper neuronal plasticity as animals age2–4.
Xin W +7 more
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Phosphorylation of the actin binding protein Drebrin at S647 and is regulated by neuronal activity and PTEN [PDF]
Defects in actin dynamics affect activity-dependent modulation of synaptic transmission and neuronal plasticity, and can cause cognitive impairment. A salient candidate actin-binding protein linking synaptic dysfunction to cognitive deficits is Drebrin ...
Rita Hendricusdottir +43 more
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CASK regulates CaMKII autophosphorylation in neuronal growth, calcium signalling and learning [PDF]
Calcium (Ca2+)/calmodulin (CaM)-dependent kinase II (CaMKII) activity plays a fundamental role in learning and memory. A key feature of CaMKII in memory formation is its ability to be regulated by autophosphorylation, which switches its activity on and ...
John M. Gillespie +5 more
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