Results 51 to 60 of about 841,514 (309)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Neuronal, synaptic and plasticity parameters.

, 2014
Neuronal, synaptic and plasticity parameters.
Lars Schwabe (369722), Youwei Zheng (523313)   +1 more
core   +1 more source

Evaluation of a Newly Developed Smartphone App for Risk Factor Management in Young Patients With Ischemic Stroke: A Pilot Study

Frontiers in Neurology, 2022
Background: Efficient treatment of modifiable vascular risk factors decreases reoccurrence of ischemic stroke, which is of uttermost importance in younger patients.
Viktoria Fruhwirth, Viktoria Fruhwirth, Lisa Berger, Lisa Berger, Thomas Gattringer, Thomas Gattringer, Simon Fandler-Höfler, Markus Kneihsl, Andreas Schwerdtfeger, Elisabeth Margarete Weiss, Christian Enzinger, Christian Enzinger, Christian Enzinger, Daniela Pinter, Daniela Pinter   +14 more
doaj   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Neuronal, synaptic, and plasticity parameters.

, 2013
Neuronal, synaptic, and plasticity parameters.
Baktash Babadi (359969), L. F. Abbott (271048)   +1 more
core   +1 more source

Imprinting and cortical plasticity: A comparative review: a comparative review [PDF]

, 1983
Bischof H-J. Imprinting and cortical plasticity: A comparative review: a comparative review. Neuroscience and Biobehavioral Reviews. 1983;7(2):213-225.Results of research on imprinting and developmental neurobiology of the visual cortex are compared to ...
Bischof, Hans-Joachim
core   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Chondroitin Sulfate Induces Depression of Synaptic Transmission and Modulation of Neuronal Plasticity in Rat Hippocampal Slices [PDF]

, 2015
It is currently known that in CNS the extracellular matrix is involved in synaptic stabilization and limitation of synaptic plasticity. However, it has been reported that the treatment with chondroitinase following injury allows the formation of new ...
Elisa Albiñana, Josep Vergés, Vergés, Josep C., Hernández Guijo, Jesús Miguel, Gutierrez-Luengo, Javier, Natalia Hernández-Juarez, Eulalia Montell, Baraibar, Andrés M., Andrés M. Baraibar, Albiñana, Elisa, García García, Antonio, Antonio G. García, Montell, Eulalia, Jesus M. Hernández-Guijo, Javier Gutierrez-Luengo, Hernández-Juárez, Natalia, Baraibar, Andrés M, Hernández-Guijo, Jesus M, García, Antonio G, Vergés, Josep   +19 more
core   +1 more source

Resting state network changes induced by experimental inaudible infrasound exposure and associations with self-reported noise sensitivity and annoyance

Scientific Reports
The effects of prolonged infrasound (IS) exposure on brain function and behavior are largely unknown, with only one prior study investigating functional connectivity (FC) changes.
Caroline Garcia Forlim, Leonie Ascone, Christian Koch, Simone Kühn   +3 more
doaj   +1 more source

Astroglial CD38 impairs hippocampal synaptic plasticity after global cerebral ischemia

Frontiers in Stroke
Cardiac arrest-induced global cerebral ischemia (GCI) results in profound cognitive impairment in survivors. Our prior work demonstrated persistent disruption of long-term potentiation (LTP) in hippocampal CA1 neurons, correlating with learning and ...
Amelia M. Burch, Ami Haas, James E. Orfila, Erika Tiemeier, Cassidy De Anda Gamboa, Nicholas Chalmers, Nidia Quillinan, Paco S. Herson   +7 more
doaj   +1 more source